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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FADS1
All Species:
35.76
Human Site:
S433
Identified Species:
87.41
UniProt:
O60427
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60427
NP_037534.3
444
51964
S433
I
I
H
S
L
K
E
S
G
Q
L
W
L
D
A
Chimpanzee
Pan troglodytes
XP_001150290
501
57825
S490
I
I
H
S
L
K
E
S
G
Q
L
W
L
D
A
Rhesus Macaque
Macaca mulatta
XP_001118502
603
68658
L546
L
F
F
I
V
R
F
L
E
S
N
W
F
V
W
Dog
Lupus familis
XP_540914
442
51890
S431
I
I
Y
S
L
K
E
S
G
Q
L
W
L
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q920L1
447
52304
S436
I
V
Y
S
L
K
E
S
G
Q
L
W
L
D
A
Rat
Rattus norvegicus
Q920R3
447
52463
S436
I
V
Y
S
L
K
E
S
G
Q
L
W
L
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512576
405
47397
S394
I
V
H
S
L
K
E
S
G
E
L
W
L
D
A
Chicken
Gallus gallus
XP_421052
508
59057
S497
I
V
Y
S
L
K
D
S
G
E
L
W
L
D
A
Frog
Xenopus laevis
Q6DDK2
446
52296
S435
V
L
R
S
L
K
K
S
G
Q
L
W
L
D
A
Zebra Danio
Brachydanio rerio
Q9DEX7
444
52013
S433
I
I
R
S
L
E
K
S
G
E
L
W
L
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.6
39.2
89.8
N.A.
88.3
88.5
N.A.
75.9
70.2
58.2
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.6
47
93.6
N.A.
94.6
94.6
N.A.
82.6
80.3
73.3
73.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
86.6
N.A.
86.6
73.3
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
90
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
90
0
% D
% Glu:
0
0
0
0
0
10
60
0
10
30
0
0
0
0
0
% E
% Phe:
0
10
10
0
0
0
10
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
90
0
0
0
0
0
0
% G
% His:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
80
40
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
80
20
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
90
0
0
10
0
0
90
0
90
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% Q
% Arg:
0
0
20
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
90
0
0
0
90
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
40
0
0
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
10
% W
% Tyr:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _