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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DFNA5 All Species: 15.15
Human Site: S429 Identified Species: 41.67
UniProt: O60443 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60443 NP_001120925.1 496 54555 S429 A L S D D G V S D L E D P T L
Chimpanzee Pan troglodytes XP_001159685 496 54750 S429 A L S D D G V S D L E D P I L
Rhesus Macaque Macaca mulatta XP_001095769 495 54674 S429 V L S D D G V S D L E D P T L
Dog Lupus familis XP_853956 503 55759 S437 A L S D N G V S D L E N P D L
Cat Felis silvestris
Mouse Mus musculus Q9Z2D3 512 56612 C432 A L S D D S V C D F H N P T L
Rat Rattus norvegicus XP_001056934 513 56882 C432 A L S D D S V C D F Q D P T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516732 160 17433 D94 I E L Y V K Q D G Q F E F C L
Chicken Gallus gallus NP_001006361 505 56046 L435 I A S A D G T L A L S S P S V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001001947 472 51189 S406 N M A L N E K S S L K D A A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 95.1 78.1 N.A. 70.1 70.7 N.A. 23.3 51.6 N.A. 35.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.9 96.9 86.4 N.A. 79.6 79.9 N.A. 27.8 68.1 N.A. 55 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 80 N.A. 66.6 73.3 N.A. 6.6 33.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 73.3 80 N.A. 13.3 46.6 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 56 12 12 12 0 0 0 0 12 0 0 0 12 12 0 % A
% Cys: 0 0 0 0 0 0 0 23 0 0 0 0 0 12 0 % C
% Asp: 0 0 0 67 67 0 0 12 67 0 0 56 0 12 0 % D
% Glu: 0 12 0 0 0 12 0 0 0 0 45 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 23 12 0 12 0 0 % F
% Gly: 0 0 0 0 0 56 0 0 12 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % H
% Ile: 23 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 0 0 0 0 12 12 0 0 0 12 0 0 0 0 % K
% Leu: 0 67 12 12 0 0 0 12 0 67 0 0 0 0 89 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 23 0 0 0 0 0 0 23 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 78 0 0 % P
% Gln: 0 0 0 0 0 0 12 0 0 12 12 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 78 0 0 23 0 56 12 0 12 12 0 12 0 % S
% Thr: 0 0 0 0 0 0 12 0 0 0 0 0 0 45 0 % T
% Val: 12 0 0 0 12 0 67 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _