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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DFNA5
All Species:
9.09
Human Site:
S458
Identified Species:
25
UniProt:
O60443
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60443
NP_001120925.1
496
54555
S458
L
F
A
S
A
D
I
S
L
E
R
L
K
S
S
Chimpanzee
Pan troglodytes
XP_001159685
496
54750
S458
L
F
A
S
A
D
I
S
L
E
R
L
K
S
S
Rhesus Macaque
Macaca mulatta
XP_001095769
495
54674
S458
L
F
A
S
A
D
I
S
L
E
R
L
K
S
S
Dog
Lupus familis
XP_853956
503
55759
N466
L
F
A
S
A
D
M
N
L
E
R
L
Q
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2D3
512
56612
A461
L
F
A
S
A
D
I
A
L
E
R
M
Q
F
S
Rat
Rattus norvegicus
XP_001056934
513
56882
A461
L
F
A
S
A
D
I
A
L
E
R
M
Q
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516732
160
17433
L123
S
L
L
H
P
N
L
L
T
S
G
E
P
T
F
Chicken
Gallus gallus
NP_001006361
505
56046
N464
L
F
A
S
A
N
I
N
L
E
K
T
E
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001001947
472
51189
M435
L
F
N
S
C
N
V
M
L
L
K
D
D
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
95.1
78.1
N.A.
70.1
70.7
N.A.
23.3
51.6
N.A.
35.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.9
96.9
86.4
N.A.
79.6
79.9
N.A.
27.8
68.1
N.A.
55
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
0
60
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
93.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
78
0
78
0
0
23
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
67
0
0
0
0
0
12
12
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
78
0
12
12
0
0
% E
% Phe:
0
89
0
0
0
0
0
0
0
0
0
0
0
23
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
23
0
34
0
0
% K
% Leu:
89
12
12
0
0
0
12
12
89
12
0
45
0
0
0
% L
% Met:
0
0
0
0
0
0
12
12
0
0
0
23
0
0
0
% M
% Asn:
0
0
12
0
0
34
0
23
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% R
% Ser:
12
0
0
89
0
0
0
34
0
12
0
0
0
45
89
% S
% Thr:
0
0
0
0
0
0
0
0
12
0
0
12
0
23
0
% T
% Val:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _