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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EVI5 All Species: 17.58
Human Site: S122 Identified Species: 55.24
UniProt: O60447 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60447 NP_005656.4 810 92935 S122 S S L V S S S S A S S N L S H
Chimpanzee Pan troglodytes XP_513563 810 93027 S122 S S L V S S S S A S S N L S H
Rhesus Macaque Macaca mulatta XP_001099693 810 92963 S122 S S L V S S S S A S S N L S H
Dog Lupus familis XP_537075 825 95145 G119 V K E L V R K G I P H H F R A
Cat Felis silvestris
Mouse Mus musculus P97366 809 92924 S122 S S L V S S S S A S S N L S H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512280 425 49637
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYY9 807 92764 P118 E L V R R G I P H H F R A I V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799050 880 100294 S194 A S Q Q S T S S S T S N L S N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.1 89.9 N.A. 89.6 N.A. N.A. 48.7 N.A. N.A. N.A. N.A. 37.9 N.A. N.A. 45.5
Protein Similarity: 100 99.7 99.5 91.1 N.A. 94.1 N.A. N.A. 50.8 N.A. N.A. N.A. N.A. 57 N.A. N.A. 63.9
P-Site Identity: 100 100 100 0 N.A. 100 N.A. N.A. 0 N.A. N.A. N.A. N.A. 0 N.A. N.A. 53.3
P-Site Similarity: 100 100 100 13.3 N.A. 100 N.A. N.A. 0 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 0 0 0 0 50 0 0 0 13 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 13 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 13 0 13 0 0 % F
% Gly: 0 0 0 0 0 13 0 13 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 13 13 13 13 0 0 50 % H
% Ile: 0 0 0 0 0 0 13 0 13 0 0 0 0 13 0 % I
% Lys: 0 13 0 0 0 0 13 0 0 0 0 0 0 0 0 % K
% Leu: 0 13 50 13 0 0 0 0 0 0 0 0 63 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 63 0 0 13 % N
% Pro: 0 0 0 0 0 0 0 13 0 13 0 0 0 0 0 % P
% Gln: 0 0 13 13 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 13 13 13 0 0 0 0 0 13 0 13 0 % R
% Ser: 50 63 0 0 63 50 63 63 13 50 63 0 0 63 0 % S
% Thr: 0 0 0 0 0 13 0 0 0 13 0 0 0 0 0 % T
% Val: 13 0 13 50 13 0 0 0 0 0 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _