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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAN1A2 All Species: 20.61
Human Site: T443 Identified Species: 45.33
UniProt: O60476 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60476 NP_006690.1 641 73004 T443 K K S R G G L T F I G E W K N
Chimpanzee Pan troglodytes XP_513685 641 72877 T443 K K S R G G L T F I G E W K N
Rhesus Macaque Macaca mulatta XP_001113249 641 72899 V443 K K S R G G L V F I G E W K N
Dog Lupus familis XP_849121 658 74973 T460 K K S R G G L T F I G E W K N
Cat Felis silvestris
Mouse Mus musculus P39098 641 72853 V443 K K S R G G L V F I G E W K N
Rat Rattus norvegicus NP_001099922 641 72810 V443 K K S R G G L V F I G E W K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511963 470 53362 A293 M G H L T C F A G G M F A L G
Chicken Gallus gallus XP_416490 643 73057 T445 R K S N G G L T F I G E W K N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923302 661 75028 T463 R K S N G G L T F I G E W K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P53624 667 74947 T464 R T S P G G L T Y V S D L K F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18788 590 66931 L403 K V S K Q S N L T Y T V E L N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 99 94.3 N.A. 94.5 95 N.A. 65.5 88.9 N.A. 80.4 N.A. 44.6 N.A. 41.6 N.A.
Protein Similarity: 100 99.5 99 95.7 N.A. 97.1 97.1 N.A. 69.1 93.7 N.A. 88.9 N.A. 62.3 N.A. 59.2 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. 0 86.6 N.A. 86.6 N.A. 40 N.A. 20 N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. 0 93.3 N.A. 93.3 N.A. 66.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 73 10 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 73 0 0 10 0 0 10 % F
% Gly: 0 10 0 0 82 82 0 0 10 10 73 0 0 0 10 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 73 0 0 0 0 0 % I
% Lys: 64 73 0 10 0 0 0 0 0 0 0 0 0 82 0 % K
% Leu: 0 0 0 10 0 0 82 10 0 0 0 0 10 19 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 19 0 0 10 0 0 0 0 0 0 0 82 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 28 0 0 55 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 91 0 0 10 0 0 0 0 10 0 0 0 0 % S
% Thr: 0 10 0 0 10 0 0 55 10 0 10 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 28 0 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 73 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _