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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZIC3
All Species:
7.88
Human Site:
S453
Identified Species:
19.26
UniProt:
O60481
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60481
NP_003404.1
467
50569
S453
S
A
V
Q
T
S
T
S
H
N
P
G
L
P
P
Chimpanzee
Pan troglodytes
XP_516806
404
43927
G391
S
A
V
H
H
T
A
G
H
S
A
L
S
S
N
Rhesus Macaque
Macaca mulatta
XP_001093759
1092
112511
A1020
S
N
L
S
P
A
A
A
A
A
A
A
A
A
A
Dog
Lupus familis
XP_549291
538
58208
T523
A
L
H
N
T
T
Y
T
K
C
R
V
N
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q62521
466
50626
S452
S
A
V
Q
T
S
T
S
H
N
P
G
L
P
P
Rat
Rattus norvegicus
NP_001102489
411
44938
L398
T
L
I
P
D
E
E
L
A
T
D
V
G
M
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507901
348
38127
A335
Y
V
C
Q
G
P
G
A
D
P
R
H
L
Y
A
Chicken
Gallus gallus
P55878
556
60197
D469
G
Q
S
S
C
S
S
D
R
S
P
L
G
S
T
Frog
Xenopus laevis
O57311
441
48466
N424
S
A
T
H
Q
T
N
N
N
S
H
N
T
G
L
Zebra Danio
Brachydanio rerio
NP_001001950
448
48862
S433
T
S
A
V
Q
N
S
S
A
H
S
D
G
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.3
31.7
75.6
N.A.
97.6
81.5
N.A.
44.9
26
76.6
75.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
68.7
35.9
76.7
N.A.
98.2
83
N.A.
53.3
38.3
84.8
84.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
6.6
6.6
N.A.
100
0
N.A.
13.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
26.6
26.6
N.A.
100
13.3
N.A.
20
26.6
40
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
40
10
0
0
10
20
20
30
10
20
10
10
20
20
% A
% Cys:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
10
0
10
10
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
10
10
0
0
0
20
30
10
0
% G
% His:
0
0
10
20
10
0
0
0
30
10
10
10
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
20
10
0
0
0
0
10
0
0
0
20
30
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
10
0
10
10
10
10
20
0
10
10
0
10
% N
% Pro:
0
0
0
10
10
10
0
0
0
10
30
0
0
20
30
% P
% Gln:
0
10
0
30
20
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
20
0
0
0
0
% R
% Ser:
50
10
10
20
0
30
20
30
0
30
10
0
10
20
0
% S
% Thr:
20
0
10
0
30
30
20
10
0
10
0
0
10
0
10
% T
% Val:
0
10
30
10
0
0
0
0
0
0
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _