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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLXNC1
All Species:
14.55
Human Site:
Y440
Identified Species:
40
UniProt:
O60486
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60486
NP_005752.1
1568
175742
Y440
P
V
K
N
I
Y
I
Y
L
T
A
G
K
E
V
Chimpanzee
Pan troglodytes
XP_509270
1568
175621
Y440
P
V
K
N
I
Y
I
Y
L
T
A
G
K
E
V
Rhesus Macaque
Macaca mulatta
XP_001105619
1568
175702
Y440
P
V
K
N
I
Y
I
Y
L
T
A
G
K
E
V
Dog
Lupus familis
XP_533732
1926
212235
L539
A
D
P
G
Y
L
Y
L
M
T
S
H
Q
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZC2
1574
176456
Y440
P
M
K
N
I
Y
I
Y
L
T
A
G
K
E
V
Rat
Rattus norvegicus
NP_001102214
669
74397
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416144
544
62609
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6BEA0
1903
213774
V504
S
D
Q
H
F
L
Y
V
M
S
E
S
Q
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4A7
2051
231661
S524
K
D
F
L
Y
V
L
S
Q
R
K
I
T
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.9
29.9
N.A.
90.2
33.6
N.A.
N.A.
29
N.A.
25.8
N.A.
23.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
99.4
45.5
N.A.
94.5
38.3
N.A.
N.A.
31.9
N.A.
44
N.A.
40.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
0
N.A.
N.A.
0
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
100
0
N.A.
N.A.
0
N.A.
33.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
45
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
12
0
0
45
0
% E
% Phe:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
0
0
45
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
45
0
45
0
0
0
0
12
0
0
0
% I
% Lys:
12
0
45
0
0
0
0
0
0
0
12
0
45
12
0
% K
% Leu:
0
0
0
12
0
23
12
12
45
0
0
0
0
12
12
% L
% Met:
0
12
0
0
0
0
0
0
23
0
0
0
0
12
0
% M
% Asn:
0
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
45
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
12
0
0
0
23
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
12
0
0
0
0
0
0
12
0
12
12
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
56
0
0
12
0
12
% T
% Val:
0
34
0
0
0
12
0
12
0
0
0
0
0
0
45
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
23
45
23
45
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _