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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSL4
All Species:
16.97
Human Site:
S249
Identified Species:
33.94
UniProt:
O60488
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60488
NP_004449.1
711
79188
S249
F
E
I
H
S
M
Q
S
V
E
E
L
G
S
N
Chimpanzee
Pan troglodytes
XP_001166229
692
77085
A258
I
I
V
H
T
M
A
A
V
E
A
L
G
A
K
Rhesus Macaque
Macaca mulatta
XP_001099465
711
79118
S249
F
E
I
H
S
M
Q
S
V
E
E
L
G
S
N
Dog
Lupus familis
XP_538140
711
79187
S249
F
E
I
H
S
M
Q
S
V
E
E
L
G
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUJ7
711
79205
S249
L
E
I
H
S
M
Q
S
V
E
E
L
G
A
K
Rat
Rattus norvegicus
O35547
670
74308
K245
S
G
S
T
G
R
P
K
G
V
M
M
H
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507836
711
79242
A249
L
E
I
H
S
M
Q
A
V
E
E
L
G
A
Q
Chicken
Gallus gallus
XP_420317
670
74487
K245
S
G
S
T
G
R
P
K
G
V
M
M
Q
H
K
Frog
Xenopus laevis
NP_001124420
670
74249
R243
Y
T
S
G
S
T
G
R
P
K
G
V
M
M
I
Zebra Danio
Brachydanio rerio
NP_956943
706
78457
S245
I
Q
I
H
S
M
H
S
V
E
E
L
G
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84P24
566
61938
Y173
V
I
S
V
S
E
S
Y
D
F
D
S
I
R
I
Baker's Yeast
Sacchar. cerevisiae
P47912
694
77249
E242
I
K
I
Y
S
F
D
E
I
I
E
I
G
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.9
99.5
97.4
N.A.
95.6
91.8
N.A.
91.5
81.7
77.6
74.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
76.2
99.7
99.3
N.A.
98.3
93.2
N.A.
96.4
87.9
86.5
86.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
100
93.3
N.A.
80
0
N.A.
73.3
0
6.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
93.3
N.A.
86.6
13.3
N.A.
86.6
6.6
26.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.4
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.6
50.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
17
0
0
9
0
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% D
% Glu:
0
42
0
0
0
9
0
9
0
59
59
0
0
0
0
% E
% Phe:
25
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
17
0
9
17
0
9
0
17
0
9
0
67
0
0
% G
% His:
0
0
0
59
0
0
9
0
0
0
0
0
9
17
0
% H
% Ile:
25
17
59
0
0
0
0
0
9
9
0
9
9
0
17
% I
% Lys:
0
9
0
0
0
0
0
17
0
9
0
0
0
9
50
% K
% Leu:
17
0
0
0
0
0
0
0
0
0
0
59
0
0
0
% L
% Met:
0
0
0
0
0
59
0
0
0
0
17
17
9
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% N
% Pro:
0
0
0
0
0
0
17
0
9
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
42
0
0
0
0
0
9
0
9
% Q
% Arg:
0
0
0
0
0
17
0
9
0
0
0
0
0
9
0
% R
% Ser:
17
0
34
0
75
0
9
42
0
0
0
9
0
25
9
% S
% Thr:
0
9
0
17
9
9
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
9
9
0
0
0
0
59
17
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _