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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACSL4 All Species: 36.36
Human Site: S584 Identified Species: 72.73
UniProt: O60488 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60488 NP_004449.1 711 79188 S584 L Q A G E Y V S L G K V E A A
Chimpanzee Pan troglodytes XP_001166229 692 77085 S593 L Q A G E Y V S L G K V E A A
Rhesus Macaque Macaca mulatta XP_001099465 711 79118 S584 L Q A G E Y V S L G K V E A A
Dog Lupus familis XP_538140 711 79187 S584 L Q A G E Y V S L G K V E A A
Cat Felis silvestris
Mouse Mus musculus Q9QUJ7 711 79205 F584 L Q A G E Y V F L G K V E A A
Rat Rattus norvegicus O35547 670 74308 S543 L Q A G E Y V S L G K V E A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507836 711 79242 S584 L Q A G E Y V S L G K V E S A
Chicken Gallus gallus XP_420317 670 74487 S543 L Q A G E Y V S L G K V E A A
Frog Xenopus laevis NP_001124420 670 74249 S543 L Q A G E Y V S L G K V E A A
Zebra Danio Brachydanio rerio NP_956943 706 78457 S579 L Q A G E Y V S L G K V E S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84P24 566 61938 A472 K G F Q I A P A D L E A V L V
Baker's Yeast Sacchar. cerevisiae P47912 694 77249 A563 T L N G E Y I A L E K L E S I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.9 99.5 97.4 N.A. 95.6 91.8 N.A. 91.5 81.7 77.6 74.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 76.2 99.7 99.3 N.A. 98.3 93.2 N.A. 96.4 87.9 86.5 86.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 93.3 100 100 93.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 100 100 100 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.4 30.6 N.A.
Protein Similarity: N.A. N.A. N.A. 40.6 50.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 84 0 0 9 0 17 0 0 0 9 0 67 84 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 92 0 0 0 0 9 9 0 92 0 0 % E
% Phe: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 92 0 0 0 0 0 84 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 9 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 92 0 0 0 0 % K
% Leu: 84 9 0 0 0 0 0 0 92 9 0 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 84 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 75 0 0 0 0 0 25 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 84 0 0 0 0 84 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 92 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _