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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSL4
All Species:
25.76
Human Site:
Y406
Identified Species:
51.52
UniProt:
O60488
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60488
NP_004449.1
711
79188
Y406
L
F
K
I
G
Y
D
Y
K
L
E
Q
I
K
K
Chimpanzee
Pan troglodytes
XP_001166229
692
77085
Y415
L
F
I
L
A
Y
N
Y
K
M
E
Q
I
S
K
Rhesus Macaque
Macaca mulatta
XP_001099465
711
79118
Y406
L
F
K
I
G
Y
D
Y
K
L
E
Q
I
K
K
Dog
Lupus familis
XP_538140
711
79187
Y406
L
F
K
L
G
Y
D
Y
K
L
E
Q
I
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUJ7
711
79205
Y406
L
F
K
I
G
Y
D
Y
K
L
E
Q
I
K
K
Rat
Rattus norvegicus
O35547
670
74308
G402
V
R
M
M
L
S
G
G
A
P
L
S
P
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507836
711
79242
Y406
L
F
K
I
G
Y
D
Y
K
L
E
Q
I
K
K
Chicken
Gallus gallus
XP_420317
670
74487
G402
I
R
M
M
L
S
G
G
A
P
L
S
P
Q
T
Frog
Xenopus laevis
NP_001124420
670
74249
C400
G
N
V
R
M
M
L
C
G
G
A
P
L
S
P
Zebra Danio
Brachydanio rerio
NP_956943
706
78457
Y402
L
F
K
P
A
Y
D
Y
K
L
E
Q
I
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84P24
566
61938
V330
V
F
K
S
L
K
Q
V
S
S
G
A
A
P
L
Baker's Yeast
Sacchar. cerevisiae
P47912
694
77249
R399
T
V
Y
A
L
K
E
R
N
I
P
C
S
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.9
99.5
97.4
N.A.
95.6
91.8
N.A.
91.5
81.7
77.6
74.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
76.2
99.7
99.3
N.A.
98.3
93.2
N.A.
96.4
87.9
86.5
86.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
93.3
N.A.
100
0
N.A.
100
0
0
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
20
N.A.
100
20
6.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.4
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.6
50.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
17
0
0
0
17
0
9
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
59
0
0
0
0
% E
% Phe:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
42
0
17
17
9
9
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
34
0
0
0
0
0
9
0
0
59
0
0
% I
% Lys:
0
0
59
0
0
17
0
0
59
0
0
0
0
50
59
% K
% Leu:
59
0
0
17
34
0
9
0
0
50
17
0
9
0
17
% L
% Met:
0
0
17
17
9
9
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
9
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
17
9
9
17
9
9
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
59
0
17
0
% Q
% Arg:
0
17
0
9
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
17
0
0
9
9
0
17
9
17
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% T
% Val:
17
9
9
0
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
59
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _