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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX10
All Species:
17.88
Human Site:
S134
Identified Species:
30.26
UniProt:
O60499
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60499
NP_003756.1
249
28114
S134
P
A
A
Q
K
S
P
S
D
L
L
D
A
S
A
Chimpanzee
Pan troglodytes
XP_001170954
249
27872
S134
P
A
A
Q
K
S
P
S
D
L
L
D
A
S
A
Rhesus Macaque
Macaca mulatta
XP_001110927
249
28138
S134
P
A
P
Q
K
S
L
S
D
L
L
D
A
S
A
Dog
Lupus familis
XP_533896
249
28374
S134
P
A
P
Q
K
S
S
S
D
L
L
D
V
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKK1
255
28978
Y140
N
A
G
V
A
D
R
Y
G
R
L
D
R
E
L
Rat
Rattus norvegicus
Q63635
255
29038
Y140
D
A
G
V
T
D
R
Y
G
R
L
D
R
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515866
288
32736
Y173
W
S
T
G
T
D
K
Y
S
R
L
D
R
E
L
Chicken
Gallus gallus
Q5ZL19
254
29137
Y139
W
S
S
G
P
D
K
Y
S
R
L
D
R
E
L
Frog
Xenopus laevis
NP_001088686
250
28950
F135
Q
Q
P
R
T
D
R
F
S
R
L
D
E
E
I
Zebra Danio
Brachydanio rerio
NP_001017879
256
29159
Y141
W
Q
P
S
G
E
K
Y
T
R
L
D
N
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393125
262
30173
A136
P
L
L
D
N
S
P
A
R
V
P
V
N
H
G
Nematode Worm
Caenorhab. elegans
P83528
122
14016
L27
P
S
S
A
N
Q
I
L
T
R
Q
E
Q
I
I
Sea Urchin
Strong. purpuratus
XP_780210
249
29158
Y135
P
G
R
P
K
H
K
Y
S
R
L
E
Q
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03322
224
25798
E110
I
P
L
E
E
T
V
E
N
S
T
L
N
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
99.1
91.9
N.A.
61.5
61.5
N.A.
53.8
61.8
61.2
60.1
N.A.
N.A.
42.7
22.4
53
Protein Similarity:
100
95.1
99.1
95.5
N.A.
76.4
75.6
N.A.
66.3
75.9
77.5
76.9
N.A.
N.A.
60.6
37.3
73.9
P-Site Identity:
100
100
86.6
73.3
N.A.
20
20
N.A.
13.3
13.3
13.3
13.3
N.A.
N.A.
20
6.6
26.6
P-Site Similarity:
100
100
86.6
73.3
N.A.
20
20
N.A.
20
26.6
20
13.3
N.A.
N.A.
33.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
15
8
8
0
0
8
0
0
0
0
22
0
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
36
0
0
29
0
0
72
0
0
0
% D
% Glu:
0
0
0
8
8
8
0
8
0
0
0
15
8
50
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
15
15
8
0
0
0
15
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
15
% I
% Lys:
0
0
0
0
36
0
29
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
15
0
0
0
8
8
0
29
79
8
0
0
36
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
15
0
0
0
8
0
0
0
22
0
0
% N
% Pro:
50
8
29
8
8
0
22
0
0
0
8
0
0
0
0
% P
% Gln:
8
15
0
29
0
8
0
0
0
0
8
0
15
0
0
% Q
% Arg:
0
0
8
8
0
0
22
0
8
58
0
0
29
0
0
% R
% Ser:
0
22
15
8
0
36
8
29
29
8
0
0
0
29
8
% S
% Thr:
0
0
8
0
22
8
0
0
15
0
8
0
0
8
0
% T
% Val:
0
0
0
15
0
0
8
0
0
8
0
8
8
0
0
% V
% Trp:
22
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _