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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX10
All Species:
13.94
Human Site:
S140
Identified Species:
23.59
UniProt:
O60499
Number Species:
13
Phosphosite Substitution
Charge Score:
0.54
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60499
NP_003756.1
249
28114
S140
P
S
D
L
L
D
A
S
A
V
S
A
T
S
R
Chimpanzee
Pan troglodytes
XP_001170954
249
27872
S140
P
S
D
L
L
D
A
S
A
V
S
A
T
S
R
Rhesus Macaque
Macaca mulatta
XP_001110927
249
28138
S140
L
S
D
L
L
D
A
S
A
V
S
A
T
S
R
Dog
Lupus familis
XP_533896
249
28374
S140
S
S
D
L
L
D
V
S
M
A
S
A
T
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKK1
255
28978
E146
R
Y
G
R
L
D
R
E
L
Q
L
A
N
S
H
Rat
Rattus norvegicus
Q63635
255
29038
E146
R
Y
G
R
L
D
R
E
L
Q
L
A
N
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515866
288
32736
E179
K
Y
S
R
L
D
R
E
L
Q
L
A
N
S
H
Chicken
Gallus gallus
Q5ZL19
254
29137
E145
K
Y
S
R
L
D
R
E
L
Q
L
A
N
S
H
Frog
Xenopus laevis
NP_001088686
250
28950
E141
R
F
S
R
L
D
E
E
I
I
S
G
N
S
R
Zebra Danio
Brachydanio rerio
NP_001017879
256
29159
E147
K
Y
T
R
L
D
N
E
L
Q
T
A
N
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393125
262
30173
H142
P
A
R
V
P
V
N
H
G
T
T
K
Y
S
K
Nematode Worm
Caenorhab. elegans
P83528
122
14016
I33
I
L
T
R
Q
E
Q
I
I
Q
E
Q
D
D
E
Sea Urchin
Strong. purpuratus
XP_780210
249
29158
E141
K
Y
S
R
L
E
Q
E
A
E
D
E
N
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03322
224
25798
T116
V
E
N
S
T
L
N
T
S
M
A
E
N
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
99.1
91.9
N.A.
61.5
61.5
N.A.
53.8
61.8
61.2
60.1
N.A.
N.A.
42.7
22.4
53
Protein Similarity:
100
95.1
99.1
95.5
N.A.
76.4
75.6
N.A.
66.3
75.9
77.5
76.9
N.A.
N.A.
60.6
37.3
73.9
P-Site Identity:
100
100
93.3
73.3
N.A.
26.6
26.6
N.A.
26.6
26.6
33.3
26.6
N.A.
N.A.
13.3
0
20
P-Site Similarity:
100
100
93.3
73.3
N.A.
26.6
26.6
N.A.
26.6
26.6
40
40
N.A.
N.A.
40
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
22
0
29
8
8
65
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
29
0
0
72
0
0
0
0
8
0
8
8
8
% D
% Glu:
0
8
0
0
0
15
8
50
0
8
8
15
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
29
% H
% Ile:
8
0
0
0
0
0
0
8
15
8
0
0
0
0
0
% I
% Lys:
29
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% K
% Leu:
8
8
0
29
79
8
0
0
36
0
29
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
22
0
0
0
0
0
58
8
0
% N
% Pro:
22
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
15
0
0
43
0
8
0
8
8
% Q
% Arg:
22
0
8
58
0
0
29
0
0
0
0
0
0
0
43
% R
% Ser:
8
29
29
8
0
0
0
29
8
0
36
0
0
79
0
% S
% Thr:
0
0
15
0
8
0
0
8
0
8
15
0
29
0
0
% T
% Val:
8
0
0
8
0
8
8
0
0
22
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
43
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _