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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX10
All Species:
42.12
Human Site:
S181
Identified Species:
71.28
UniProt:
O60499
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60499
NP_003756.1
249
28114
S181
I
Q
V
L
K
H
M
S
G
R
V
G
E
E
L
Chimpanzee
Pan troglodytes
XP_001170954
249
27872
S181
I
Q
V
L
K
H
M
S
G
R
V
G
E
E
L
Rhesus Macaque
Macaca mulatta
XP_001110927
249
28138
S181
I
Q
V
L
K
H
M
S
G
R
V
G
E
E
L
Dog
Lupus familis
XP_533896
249
28374
S181
I
R
V
L
K
H
M
S
G
R
V
G
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKK1
255
28978
S187
I
G
V
L
K
N
M
S
Q
R
I
G
G
E
L
Rat
Rattus norvegicus
Q63635
255
29038
S187
I
G
V
L
K
N
M
S
Q
R
I
G
G
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515866
288
32736
S220
I
G
V
L
K
N
M
S
Q
R
I
G
G
E
L
Chicken
Gallus gallus
Q5ZL19
254
29137
S186
I
G
V
L
K
N
M
S
Q
R
I
G
G
E
L
Frog
Xenopus laevis
NP_001088686
250
28950
S182
I
R
V
L
K
D
M
S
S
R
I
G
D
E
L
Zebra Danio
Brachydanio rerio
NP_001017879
256
29159
S188
I
G
V
L
K
N
M
S
Q
R
I
G
Q
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393125
262
30173
S194
I
G
T
L
K
T
V
S
R
Q
I
N
T
E
L
Nematode Worm
Caenorhab. elegans
P83528
122
14016
G73
S
T
M
L
D
D
L
G
Q
E
M
E
Y
S
E
Sea Urchin
Strong. purpuratus
XP_780210
249
29158
S182
V
G
V
L
K
N
M
S
H
S
I
G
N
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03322
224
25798
A156
M
Q
N
L
H
I
Q
A
Q
T
M
G
D
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
99.1
91.9
N.A.
61.5
61.5
N.A.
53.8
61.8
61.2
60.1
N.A.
N.A.
42.7
22.4
53
Protein Similarity:
100
95.1
99.1
95.5
N.A.
76.4
75.6
N.A.
66.3
75.9
77.5
76.9
N.A.
N.A.
60.6
37.3
73.9
P-Site Identity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
66.6
66.6
66.6
66.6
N.A.
N.A.
40
6.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
80
80
86.6
86.6
N.A.
N.A.
60
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
15
0
0
0
0
0
0
15
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
8
29
93
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
0
0
0
8
29
0
0
86
29
0
0
% G
% His:
0
0
0
0
8
29
0
0
8
0
0
0
0
0
0
% H
% Ile:
79
0
0
0
0
8
0
0
0
0
58
0
0
0
0
% I
% Lys:
0
0
0
0
86
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
100
0
0
8
0
0
0
0
0
0
0
93
% L
% Met:
8
0
8
0
0
0
79
0
0
0
15
0
0
0
0
% M
% Asn:
0
0
8
0
0
43
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
29
0
0
0
0
8
0
50
8
0
0
8
0
0
% Q
% Arg:
0
15
0
0
0
0
0
0
8
72
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
86
8
8
0
0
0
8
0
% S
% Thr:
0
8
8
0
0
8
0
0
0
8
0
0
8
0
0
% T
% Val:
8
0
79
0
0
0
8
0
0
0
29
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _