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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX10
All Species:
44.85
Human Site:
S220
Identified Species:
75.9
UniProt:
O60499
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60499
NP_003756.1
249
28114
S220
L
R
K
L
A
K
V
S
H
M
T
S
D
R
R
Chimpanzee
Pan troglodytes
XP_001170954
249
27872
S220
L
R
K
L
A
K
V
S
H
M
T
S
D
R
R
Rhesus Macaque
Macaca mulatta
XP_001110927
249
28138
S220
L
R
K
L
A
K
V
S
H
M
T
S
D
R
R
Dog
Lupus familis
XP_533896
249
28374
S220
L
R
K
M
A
K
V
S
H
M
T
S
D
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKK1
255
28978
S226
M
K
K
L
A
K
V
S
H
M
T
S
D
R
R
Rat
Rattus norvegicus
Q63635
255
29038
S226
M
K
K
L
A
K
V
S
H
M
T
S
D
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515866
288
32736
S259
M
K
K
L
A
K
V
S
H
M
T
S
D
R
R
Chicken
Gallus gallus
Q5ZL19
254
29137
S225
M
K
K
L
A
K
V
S
H
M
T
S
D
R
R
Frog
Xenopus laevis
NP_001088686
250
28950
S221
F
K
R
M
A
K
V
S
H
I
S
N
D
R
R
Zebra Danio
Brachydanio rerio
NP_001017879
256
29159
S227
M
K
K
L
A
K
V
S
H
M
T
S
D
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393125
262
30173
L233
M
K
K
M
A
K
V
L
H
M
S
N
D
R
R
Nematode Worm
Caenorhab. elegans
P83528
122
14016
C103
L
E
D
E
S
S
Q
C
K
M
I
M
V
L
S
Sea Urchin
Strong. purpuratus
XP_780210
249
29158
T221
M
K
K
M
A
K
V
T
R
M
S
N
D
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03322
224
25798
R188
V
N
K
L
A
R
G
R
R
Q
L
E
W
V
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
99.1
91.9
N.A.
61.5
61.5
N.A.
53.8
61.8
61.2
60.1
N.A.
N.A.
42.7
22.4
53
Protein Similarity:
100
95.1
99.1
95.5
N.A.
76.4
75.6
N.A.
66.3
75.9
77.5
76.9
N.A.
N.A.
60.6
37.3
73.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
86.6
86.6
53.3
80
N.A.
N.A.
60
13.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
N.A.
93.3
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
93
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
86
0
0
% D
% Glu:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
79
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
58
86
0
0
86
0
0
8
0
0
0
0
15
0
% K
% Leu:
36
0
0
65
0
0
0
8
0
0
8
0
0
8
0
% L
% Met:
50
0
0
29
0
0
0
0
0
86
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
22
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% Q
% Arg:
0
29
8
0
0
8
0
8
15
0
0
0
0
72
86
% R
% Ser:
0
0
0
0
8
8
0
72
0
0
22
65
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
65
0
0
0
0
% T
% Val:
8
0
0
0
0
0
86
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _