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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX10 All Species: 18.79
Human Site: T110 Identified Species: 31.79
UniProt: O60499 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60499 NP_003756.1 249 28114 T110 K D H M V S P T A V A F L E R
Chimpanzee Pan troglodytes XP_001170954 249 27872 T110 K D H M V S P T A V A F L E R
Rhesus Macaque Macaca mulatta XP_001110927 249 28138 T110 K D H M V S P T A V A F L E R
Dog Lupus familis XP_533896 249 28374 A110 K D H M V S P A A I A F M E R
Cat Felis silvestris
Mouse Mus musculus Q9JKK1 255 28978 S110 K D Q M S A S S V Q A L A E R
Rat Rattus norvegicus Q63635 255 29038 S110 K D Q M S A S S V Q A L A E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515866 288 32736 S144 K D Q M S S S S V Q A L T E R
Chicken Gallus gallus Q5ZL19 254 29137 S110 K D Q M S N S S M Q A L A E R
Frog Xenopus laevis NP_001088686 250 28950 R110 R D H I S S P R S V A F T E R
Zebra Danio Brachydanio rerio NP_001017879 256 29159 M110 K D H M T S P M A I T V P E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393125 262 30173 K111 R E E V K T M K D K M N L S R
Nematode Worm Caenorhab. elegans P83528 122 14016 N10 N Y R Y S K L N E E E I S L E
Sea Urchin Strong. purpuratus XP_780210 249 29158 G110 K E H M S S P G T K T R E D K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03322 224 25798 R90 Q L D A L K L R F D R R I Q E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 99.1 91.9 N.A. 61.5 61.5 N.A. 53.8 61.8 61.2 60.1 N.A. N.A. 42.7 22.4 53
Protein Similarity: 100 95.1 99.1 95.5 N.A. 76.4 75.6 N.A. 66.3 75.9 77.5 76.9 N.A. N.A. 60.6 37.3 73.9
P-Site Identity: 100 100 100 80 N.A. 40 40 N.A. 46.6 40 60 53.3 N.A. N.A. 13.3 0 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 53.3 53.3 N.A. 53.3 53.3 80 66.6 N.A. N.A. 40 0 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 15 0 8 36 0 65 0 22 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 72 8 0 0 0 0 0 8 8 0 0 0 8 0 % D
% Glu: 0 15 8 0 0 0 0 0 8 8 8 0 8 72 15 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 36 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 15 0 8 8 0 0 % I
% Lys: 72 0 0 0 8 15 0 8 0 15 0 0 0 0 15 % K
% Leu: 0 8 0 0 8 0 15 0 0 0 0 29 29 8 0 % L
% Met: 0 0 0 72 0 0 8 8 8 0 8 0 8 0 0 % M
% Asn: 8 0 0 0 0 8 0 8 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 50 0 0 0 0 0 8 0 0 % P
% Gln: 8 0 29 0 0 0 0 0 0 29 0 0 0 8 0 % Q
% Arg: 15 0 8 0 0 0 0 15 0 0 8 15 0 0 72 % R
% Ser: 0 0 0 0 50 58 29 29 8 0 0 0 8 8 0 % S
% Thr: 0 0 0 0 8 8 0 22 8 0 15 0 15 0 0 % T
% Val: 0 0 0 8 29 0 0 0 22 29 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _