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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHS1
All Species:
10
Human Site:
S1058
Identified Species:
24.44
UniProt:
O60500
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60500
NP_004637.1
1241
134742
S1058
T
E
P
P
S
G
P
S
G
L
P
L
L
P
V
Chimpanzee
Pan troglodytes
XP_524228
1241
134508
S1058
T
E
P
P
S
G
P
S
G
L
P
L
L
P
V
Rhesus Macaque
Macaca mulatta
XP_001112314
1052
113512
V880
F
T
W
T
K
N
G
V
P
L
D
L
Q
D
P
Dog
Lupus familis
XP_541685
1242
135134
S1058
T
E
Q
P
V
G
P
S
G
L
P
L
L
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZS7
1242
134872
P1058
T
E
Q
P
P
G
P
P
R
L
P
Q
L
P
V
Rat
Rattus norvegicus
Q9R044
1234
134286
P1054
T
E
L
P
P
G
P
P
R
L
P
L
L
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001035777
1242
137333
G1038
D
S
A
L
A
G
G
G
L
P
V
Y
V
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08180
764
82987
S592
L
E
P
G
D
R
T
S
N
Y
S
D
L
K
V
Honey Bee
Apis mellifera
XP_624127
1307
143527
L1117
K
T
A
A
S
T
Y
L
I
D
Q
T
M
Q
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796903
1010
110769
I838
I
K
K
T
N
D
E
I
E
L
V
K
P
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80.9
87
N.A.
82.5
81.8
N.A.
N.A.
N.A.
N.A.
38.8
N.A.
20.9
26.9
N.A.
21.1
Protein Similarity:
100
99.5
83
92.6
N.A.
89.6
89.3
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
33.6
42.9
N.A.
35.9
P-Site Identity:
100
100
13.3
86.6
N.A.
66.6
73.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
33.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
86.6
N.A.
66.6
73.3
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
33.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
10
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
10
0
0
0
10
10
10
0
10
10
% D
% Glu:
0
60
0
0
0
0
10
0
10
0
0
0
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
60
20
10
30
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% I
% Lys:
10
10
10
0
10
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
10
0
10
10
0
0
0
10
10
70
0
50
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% M
% Asn:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
30
50
20
0
50
20
10
10
50
0
10
50
10
% P
% Gln:
0
0
20
0
0
0
0
0
0
0
10
10
10
10
0
% Q
% Arg:
0
0
0
0
0
10
0
0
20
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
30
0
0
40
0
0
10
0
0
0
0
% S
% Thr:
50
20
0
20
0
10
10
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
10
0
0
10
0
0
20
0
10
10
70
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _