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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY9
All Species:
18.18
Human Site:
S1257
Identified Species:
33.33
UniProt:
O60503
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60503
NP_001107.2
1353
150701
S1257
V
I
P
Q
H
Q
L
S
I
S
P
D
I
R
V
Chimpanzee
Pan troglodytes
XP_510775
1356
150504
S1260
V
I
P
Q
H
Q
L
S
I
S
P
D
I
R
V
Rhesus Macaque
Macaca mulatta
XP_001095164
805
89192
R724
Q
V
D
G
S
I
G
R
S
P
T
D
E
I
A
Dog
Lupus familis
XP_547151
1352
150601
S1256
A
V
P
Q
H
Q
L
S
I
S
P
D
I
R
V
Cat
Felis silvestris
Mouse
Mus musculus
P51830
1353
150936
S1257
V
V
P
Q
H
Q
L
S
I
S
P
D
I
R
V
Rat
Rattus norvegicus
P26769
1090
123297
V1009
H
G
P
V
I
A
G
V
I
G
A
Q
K
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511444
787
88031
R706
Q
V
D
G
S
I
G
R
S
P
T
D
E
I
A
Chicken
Gallus gallus
Q9DGG6
1334
149273
S1239
I
V
P
H
H
Q
L
S
I
S
P
D
I
R
V
Frog
Xenopus laevis
P98999
1305
145393
N1221
F
D
Y
R
G
T
V
N
V
K
G
K
G
Q
M
Zebra Danio
Brachydanio rerio
XP_002661140
597
66839
M516
F
C
Q
E
K
K
E
M
V
N
M
R
V
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624914
729
83737
T648
G
F
N
Y
G
D
V
T
A
G
V
I
G
A
T
Nematode Worm
Caenorhab. elegans
NP_497970
1253
140709
I1168
G
P
V
T
A
G
V
I
G
T
T
K
L
Y
Y
Sea Urchin
Strong. purpuratus
XP_798394
1073
120672
L992
I
G
Y
N
H
G
K
L
T
S
G
V
I
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
58.6
92.9
N.A.
92.1
26
N.A.
47.3
80.4
69.9
21.3
N.A.
N.A.
23.2
35.2
34.5
Protein Similarity:
100
98.5
59
95.5
N.A.
95.4
43.5
N.A.
52.4
86.8
78.6
30.6
N.A.
N.A.
36.5
52.4
49.9
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
13.3
N.A.
6.6
80
0
0
N.A.
N.A.
0
0
20
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
13.3
N.A.
13.3
93.3
40
40
N.A.
N.A.
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
0
0
8
0
8
0
0
8
16
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
16
0
0
8
0
0
0
0
0
54
0
0
0
% D
% Glu:
0
0
0
8
0
0
8
0
0
0
0
0
16
0
0
% E
% Phe:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
16
0
16
16
16
24
0
8
16
16
0
16
16
0
% G
% His:
8
0
0
8
47
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
16
0
0
8
16
0
8
47
0
0
8
47
16
8
% I
% Lys:
0
0
0
0
8
8
8
0
0
8
0
16
8
0
0
% K
% Leu:
0
0
0
0
0
0
39
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% M
% Asn:
0
0
8
8
0
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
8
47
0
0
0
0
0
0
16
39
0
0
8
0
% P
% Gln:
16
0
8
31
0
39
0
0
0
0
0
8
0
8
8
% Q
% Arg:
0
0
0
8
0
0
0
16
0
0
0
8
0
39
0
% R
% Ser:
0
0
0
0
16
0
0
39
16
47
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
8
0
8
8
8
24
0
0
0
16
% T
% Val:
24
39
8
8
0
0
24
8
16
0
8
8
8
0
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
8
0
0
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _