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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY9
All Species:
23.33
Human Site:
S751
Identified Species:
42.78
UniProt:
O60503
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60503
NP_001107.2
1353
150701
S751
K
P
P
I
N
Q
F
S
L
N
F
L
D
Q
E
Chimpanzee
Pan troglodytes
XP_510775
1356
150504
S754
P
P
H
L
A
R
F
S
L
S
F
C
R
F
H
Rhesus Macaque
Macaca mulatta
XP_001095164
805
89192
T266
L
K
Y
E
A
A
T
T
P
P
P
P
A
A
L
Dog
Lupus familis
XP_547151
1352
150601
S751
K
P
P
I
N
E
F
S
L
N
F
L
D
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
P51830
1353
150936
S751
K
P
P
I
N
Q
F
S
L
N
F
L
D
Q
E
Rat
Rattus norvegicus
P26769
1090
123297
E551
Q
K
K
R
F
E
E
E
L
N
E
R
M
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511444
787
88031
S248
F
L
K
H
G
T
A
S
L
S
P
P
P
A
A
Chicken
Gallus gallus
Q9DGG6
1334
149273
S733
K
P
P
I
S
K
L
S
L
N
F
L
D
Q
D
Frog
Xenopus laevis
P98999
1305
145393
S743
K
P
P
I
N
P
L
S
L
N
F
L
D
K
E
Zebra Danio
Brachydanio rerio
XP_002661140
597
66839
S58
K
H
C
K
Y
S
I
S
S
S
C
S
S
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624914
729
83737
P190
P
S
S
S
V
P
Y
P
F
P
P
A
V
T
D
Nematode Worm
Caenorhab. elegans
NP_497970
1253
140709
F702
E
G
G
F
D
K
G
F
W
N
H
H
D
S
L
Sea Urchin
Strong. purpuratus
XP_798394
1073
120672
T534
P
N
T
E
N
Q
L
T
K
F
L
K
E
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
58.6
92.9
N.A.
92.1
26
N.A.
47.3
80.4
69.9
21.3
N.A.
N.A.
23.2
35.2
34.5
Protein Similarity:
100
98.5
59
95.5
N.A.
95.4
43.5
N.A.
52.4
86.8
78.6
30.6
N.A.
N.A.
36.5
52.4
49.9
P-Site Identity:
100
33.3
0
93.3
N.A.
100
13.3
N.A.
13.3
73.3
80
20
N.A.
N.A.
0
13.3
13.3
P-Site Similarity:
100
53.3
6.6
100
N.A.
100
33.3
N.A.
20
93.3
86.6
26.6
N.A.
N.A.
13.3
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
8
8
0
0
0
0
8
8
16
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
47
8
16
% D
% Glu:
8
0
0
16
0
16
8
8
0
0
8
0
8
0
39
% E
% Phe:
8
0
0
8
8
0
31
8
8
8
47
0
0
8
0
% F
% Gly:
0
8
8
0
8
0
8
0
0
0
0
0
0
8
8
% G
% His:
0
8
8
8
0
0
0
0
0
0
8
8
0
0
8
% H
% Ile:
0
0
0
39
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
47
16
16
8
0
16
0
0
8
0
0
8
0
8
0
% K
% Leu:
8
8
0
8
0
0
24
0
62
0
8
39
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
39
0
0
0
0
54
0
0
0
0
0
% N
% Pro:
24
47
39
0
0
16
0
8
8
16
24
16
8
0
0
% P
% Gln:
8
0
0
0
0
24
0
0
0
0
0
0
0
31
8
% Q
% Arg:
0
0
0
8
0
8
0
0
0
0
0
8
8
0
0
% R
% Ser:
0
8
8
8
8
8
0
62
8
24
0
8
8
8
0
% S
% Thr:
0
0
8
0
0
8
8
16
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _