KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY9
All Species:
8.79
Human Site:
S976
Identified Species:
16.11
UniProt:
O60503
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60503
NP_001107.2
1353
150701
S976
R
D
L
R
R
P
A
S
L
I
G
Q
E
V
V
Chimpanzee
Pan troglodytes
XP_510775
1356
150504
S979
R
D
L
R
R
P
A
S
L
I
G
Q
E
V
V
Rhesus Macaque
Macaca mulatta
XP_001095164
805
89192
L484
R
D
Q
A
D
W
L
L
R
N
I
I
P
Y
H
Dog
Lupus familis
XP_547151
1352
150601
L976
R
D
G
R
T
A
S
L
I
G
Q
E
V
I
L
Cat
Felis silvestris
Mouse
Mus musculus
P51830
1353
150936
S976
Q
D
G
R
R
P
A
S
L
I
G
K
E
L
I
Rat
Rattus norvegicus
P26769
1090
123297
L769
M
L
I
M
M
V
A
L
V
G
Y
N
T
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511444
787
88031
L466
R
D
Q
A
D
W
L
L
R
N
I
I
P
Y
H
Chicken
Gallus gallus
Q9DGG6
1334
149273
D958
A
D
V
K
R
P
A
D
L
I
G
Q
E
V
I
Frog
Xenopus laevis
P98999
1305
145393
R968
R
T
E
L
P
F
T
R
L
G
Q
E
I
A
V
Zebra Danio
Brachydanio rerio
XP_002661140
597
66839
L276
L
G
L
I
Y
S
V
L
F
E
T
L
G
W
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624914
729
83737
L408
N
C
W
M
K
N
F
L
V
T
F
M
G
V
L
Nematode Worm
Caenorhab. elegans
NP_497970
1253
140709
F920
A
G
V
F
Y
C
E
F
N
L
K
H
L
V
E
Sea Urchin
Strong. purpuratus
XP_798394
1073
120672
I752
I
L
M
V
L
L
F
I
C
R
S
C
P
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
58.6
92.9
N.A.
92.1
26
N.A.
47.3
80.4
69.9
21.3
N.A.
N.A.
23.2
35.2
34.5
Protein Similarity:
100
98.5
59
95.5
N.A.
95.4
43.5
N.A.
52.4
86.8
78.6
30.6
N.A.
N.A.
36.5
52.4
49.9
P-Site Identity:
100
100
13.3
20
N.A.
66.6
6.6
N.A.
13.3
66.6
20
6.6
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
100
100
13.3
53.3
N.A.
93.3
33.3
N.A.
13.3
86.6
26.6
13.3
N.A.
N.A.
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
16
0
8
39
0
0
0
0
0
0
8
0
% A
% Cys:
0
8
0
0
0
8
0
0
8
0
0
8
0
0
0
% C
% Asp:
0
54
0
0
16
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
8
0
16
31
0
8
% E
% Phe:
0
0
0
8
0
8
16
8
8
0
8
0
0
0
0
% F
% Gly:
0
16
16
0
0
0
0
0
0
24
31
0
16
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
16
% H
% Ile:
8
0
8
8
0
0
0
8
8
31
16
16
8
16
16
% I
% Lys:
0
0
0
8
8
0
0
0
0
0
8
8
0
0
0
% K
% Leu:
8
16
24
8
8
8
16
47
39
8
0
8
8
8
24
% L
% Met:
8
0
8
16
8
0
0
0
0
0
0
8
0
0
16
% M
% Asn:
8
0
0
0
0
8
0
0
8
16
0
8
0
0
0
% N
% Pro:
0
0
0
0
8
31
0
0
0
0
0
0
24
0
0
% P
% Gln:
8
0
16
0
0
0
0
0
0
0
16
24
0
0
0
% Q
% Arg:
47
0
0
31
31
0
0
8
16
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
8
24
0
0
8
0
0
0
0
% S
% Thr:
0
8
0
0
8
0
8
0
0
8
8
0
8
0
0
% T
% Val:
0
0
16
8
0
8
8
0
16
0
0
0
8
47
24
% V
% Trp:
0
0
8
0
0
16
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
16
0
0
0
0
0
8
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _