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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY9
All Species:
13.64
Human Site:
T636
Identified Species:
25
UniProt:
O60503
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60503
NP_001107.2
1353
150701
T636
T
C
P
S
C
G
I
T
F
A
P
K
S
E
A
Chimpanzee
Pan troglodytes
XP_510775
1356
150504
T636
T
C
P
S
C
G
I
T
F
A
P
K
S
E
A
Rhesus Macaque
Macaca mulatta
XP_001095164
805
89192
G156
Q
E
K
G
R
W
A
G
V
S
L
D
Q
S
A
Dog
Lupus familis
XP_547151
1352
150601
T636
T
C
P
S
C
G
I
T
F
A
P
K
S
E
A
Cat
Felis silvestris
Mouse
Mus musculus
P51830
1353
150936
T636
T
C
P
S
C
G
I
T
F
A
P
K
S
E
A
Rat
Rattus norvegicus
P26769
1090
123297
E441
L
N
G
A
Y
K
V
E
E
G
D
G
E
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511444
787
88031
A138
L
Q
E
K
G
R
W
A
G
V
S
L
D
Q
S
Chicken
Gallus gallus
Q9DGG6
1334
149273
P621
S
C
S
T
T
L
V
P
P
C
D
V
S
I
D
Frog
Xenopus laevis
P98999
1305
145393
A630
P
S
C
G
E
T
A
A
R
D
G
P
E
E
G
Zebra Danio
Brachydanio rerio
XP_002661140
597
66839
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624914
729
83737
A80
E
E
A
K
A
I
I
A
E
Q
S
K
T
E
S
Nematode Worm
Caenorhab. elegans
NP_497970
1253
140709
K591
C
I
M
E
D
N
R
K
S
A
S
L
Q
A
L
Sea Urchin
Strong. purpuratus
XP_798394
1073
120672
R424
M
E
D
T
D
S
E
R
G
E
G
S
E
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
58.6
92.9
N.A.
92.1
26
N.A.
47.3
80.4
69.9
21.3
N.A.
N.A.
23.2
35.2
34.5
Protein Similarity:
100
98.5
59
95.5
N.A.
95.4
43.5
N.A.
52.4
86.8
78.6
30.6
N.A.
N.A.
36.5
52.4
49.9
P-Site Identity:
100
100
6.6
100
N.A.
100
0
N.A.
0
13.3
6.6
0
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
13.3
N.A.
13.3
33.3
6.6
0
N.A.
N.A.
33.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
16
24
0
39
0
0
0
16
47
% A
% Cys:
8
39
8
0
31
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
0
16
0
0
0
0
8
16
8
8
0
8
% D
% Glu:
8
24
8
8
8
0
8
8
16
8
0
0
24
47
0
% E
% Phe:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
0
% F
% Gly:
0
0
8
16
8
31
0
8
16
8
16
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
39
0
0
0
0
0
0
16
0
% I
% Lys:
0
0
8
16
0
8
0
8
0
0
0
39
0
0
0
% K
% Leu:
16
0
0
0
0
8
0
0
0
0
8
16
0
0
8
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
31
0
0
0
0
8
8
0
31
8
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
8
0
0
16
8
0
% Q
% Arg:
0
0
0
0
8
8
8
8
8
0
0
0
0
0
8
% R
% Ser:
8
8
8
31
0
8
0
0
8
8
24
8
39
8
16
% S
% Thr:
31
0
0
16
8
8
0
31
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
16
0
8
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _