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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPST1
All Species:
30.3
Human Site:
S115
Identified Species:
60.61
UniProt:
O60507
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60507
NP_003587.1
370
42188
S115
L
A
L
K
Q
M
W
S
R
S
S
K
E
K
I
Chimpanzee
Pan troglodytes
XP_001172350
377
41866
S114
L
A
M
R
Q
A
W
S
K
S
G
R
E
K
L
Rhesus Macaque
Macaca mulatta
XP_001086632
370
42168
S115
L
A
L
K
Q
M
W
S
R
S
S
K
E
K
I
Dog
Lupus familis
XP_546906
370
42192
S115
L
A
L
K
Q
M
W
S
R
S
S
K
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
O70281
370
42114
S115
L
A
L
K
Q
M
W
S
R
S
S
K
E
K
I
Rat
Rattus norvegicus
Q3KR92
370
42117
S115
L
A
L
K
Q
M
W
S
R
S
S
K
E
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJI0
371
42023
S112
L
A
M
R
Q
A
W
S
K
S
G
R
E
K
M
Frog
Xenopus laevis
NP_001085590
372
42191
A113
L
A
V
K
Q
M
W
A
R
S
S
K
E
K
I
Zebra Danio
Brachydanio rerio
Q9PTE6
355
40179
S112
L
A
M
K
Q
M
W
S
R
S
G
R
E
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYB7
499
58032
L116
L
Q
L
R
S
H
W
L
K
S
E
K
E
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77081
380
43295
K115
L
N
L
R
S
Q
W
K
K
S
E
K
E
W
N
Sea Urchin
Strong. purpuratus
XP_001190618
798
90248
I105
L
S
M
R
A
Q
W
I
R
S
S
K
E
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.1
99.1
97.5
N.A.
96.4
96.2
N.A.
N.A.
64.9
87.3
79.7
N.A.
44.6
N.A.
52.1
28.9
Protein Similarity:
100
77.4
99.7
99.7
N.A.
98.3
98.6
N.A.
N.A.
79.7
93.5
88.6
N.A.
56.9
N.A.
69.2
36.5
P-Site Identity:
100
53.3
100
100
N.A.
100
100
N.A.
N.A.
53.3
86.6
73.3
N.A.
40
N.A.
40
46.6
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
100
93.3
N.A.
60
N.A.
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
75
0
0
9
17
0
9
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
17
0
100
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
50
% I
% Lys:
0
0
0
59
0
0
0
9
34
0
0
75
0
75
0
% K
% Leu:
100
0
59
0
0
0
0
9
0
0
0
0
0
0
17
% L
% Met:
0
0
34
0
0
59
0
0
0
0
0
0
0
0
17
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
75
17
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
42
0
0
0
0
67
0
0
25
0
0
0
% R
% Ser:
0
9
0
0
17
0
0
67
0
100
59
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
100
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _