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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPST1
All Species:
43.03
Human Site:
S281
Identified Species:
86.06
UniProt:
O60507
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60507
NP_003587.1
370
42188
S281
K
A
G
G
V
S
L
S
K
V
E
R
S
T
D
Chimpanzee
Pan troglodytes
XP_001172350
377
41866
S280
K
P
G
G
V
S
L
S
K
I
E
R
S
T
D
Rhesus Macaque
Macaca mulatta
XP_001086632
370
42168
S281
K
A
G
G
V
S
L
S
K
V
E
R
S
T
D
Dog
Lupus familis
XP_546906
370
42192
S281
K
A
G
G
V
S
L
S
K
V
E
R
S
T
D
Cat
Felis silvestris
Mouse
Mus musculus
O70281
370
42114
S281
K
A
G
G
V
S
L
S
K
V
E
R
S
T
D
Rat
Rattus norvegicus
Q3KR92
370
42117
S281
K
A
G
G
V
S
L
S
K
V
E
R
S
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJI0
371
42023
S278
K
P
G
G
V
S
L
S
K
I
E
R
S
T
D
Frog
Xenopus laevis
NP_001085590
372
42191
S279
K
V
G
G
I
S
L
S
K
V
E
R
S
T
D
Zebra Danio
Brachydanio rerio
Q9PTE6
355
40179
S277
K
A
G
G
V
S
L
S
K
V
E
R
S
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYB7
499
58032
S282
K
P
N
G
V
P
L
S
K
V
E
R
S
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77081
380
43295
V281
K
D
I
S
L
S
N
V
E
R
S
S
D
Q
V
Sea Urchin
Strong. purpuratus
XP_001190618
798
90248
S271
K
P
G
G
I
S
L
S
R
K
E
K
S
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.1
99.1
97.5
N.A.
96.4
96.2
N.A.
N.A.
64.9
87.3
79.7
N.A.
44.6
N.A.
52.1
28.9
Protein Similarity:
100
77.4
99.7
99.7
N.A.
98.3
98.6
N.A.
N.A.
79.7
93.5
88.6
N.A.
56.9
N.A.
69.2
36.5
P-Site Identity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
100
N.A.
73.3
N.A.
13.3
66.6
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
100
N.A.
80
N.A.
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
92
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
92
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
84
92
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
17
0
0
0
0
17
0
0
0
0
0
% I
% Lys:
100
0
0
0
0
0
0
0
84
9
0
9
0
0
0
% K
% Leu:
0
0
0
0
9
0
92
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
34
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
9
0
84
0
0
0
% R
% Ser:
0
0
0
9
0
92
0
92
0
0
9
9
92
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
84
0
% T
% Val:
0
9
0
0
75
0
0
9
0
67
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _