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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPST1
All Species:
22.12
Human Site:
S39
Identified Species:
44.24
UniProt:
O60507
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60507
NP_003587.1
370
42188
S39
H
H
R
I
E
E
R
S
Q
P
V
K
L
E
S
Chimpanzee
Pan troglodytes
XP_001172350
377
41866
L38
C
R
A
V
L
A
G
L
R
S
P
R
G
A
M
Rhesus Macaque
Macaca mulatta
XP_001086632
370
42168
S39
H
H
R
I
E
E
R
S
Q
P
V
K
L
E
S
Dog
Lupus familis
XP_546906
370
42192
S39
H
H
R
I
E
E
R
S
Q
P
L
R
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
O70281
370
42114
S39
H
H
R
I
E
E
R
S
Q
P
A
R
L
E
N
Rat
Rattus norvegicus
Q3KR92
370
42117
S39
H
H
R
I
E
E
R
S
Q
P
A
R
L
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJI0
371
42023
S36
L
E
C
Q
H
V
L
S
K
R
R
H
R
L
M
Frog
Xenopus laevis
NP_001085590
372
42191
S39
H
H
R
I
E
E
R
S
Q
P
A
K
T
E
N
Zebra Danio
Brachydanio rerio
Q9PTE6
355
40179
E36
M
D
C
H
H
R
I
E
E
R
S
Q
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYB7
499
58032
D40
P
T
C
L
F
K
V
D
A
A
N
E
L
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77081
380
43295
F39
Y
S
N
H
R
E
K
F
N
G
A
A
A
D
D
Sea Urchin
Strong. purpuratus
XP_001190618
798
90248
G29
M
L
M
H
S
N
C
G
D
T
T
E
N
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.1
99.1
97.5
N.A.
96.4
96.2
N.A.
N.A.
64.9
87.3
79.7
N.A.
44.6
N.A.
52.1
28.9
Protein Similarity:
100
77.4
99.7
99.7
N.A.
98.3
98.6
N.A.
N.A.
79.7
93.5
88.6
N.A.
56.9
N.A.
69.2
36.5
P-Site Identity:
100
0
100
86.6
N.A.
80
80
N.A.
N.A.
6.6
80
0
N.A.
13.3
N.A.
6.6
0
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
86.6
13.3
N.A.
33.3
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
0
0
9
9
34
9
9
9
0
% A
% Cys:
9
0
25
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
9
9
0
0
0
0
9
9
% D
% Glu:
0
9
0
0
50
59
0
9
9
0
0
17
0
50
0
% E
% Phe:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
9
0
9
0
0
9
0
0
% G
% His:
50
50
0
25
17
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
50
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
9
0
9
0
0
25
0
0
0
% K
% Leu:
9
9
0
9
9
0
9
9
0
0
9
0
50
17
9
% L
% Met:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
17
% M
% Asn:
0
0
9
0
0
9
0
0
9
0
9
0
9
0
25
% N
% Pro:
9
0
0
0
0
0
0
0
0
50
9
0
9
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
50
0
0
9
0
0
0
% Q
% Arg:
0
9
50
0
9
9
50
0
9
17
9
34
9
0
9
% R
% Ser:
0
9
0
0
9
0
0
59
0
9
9
0
0
9
34
% S
% Thr:
0
9
0
0
0
0
0
0
0
9
9
0
9
0
0
% T
% Val:
0
0
0
9
0
9
9
0
0
0
17
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _