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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPST1 All Species: 50
Human Site: T101 Identified Species: 100
UniProt: O60507 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60507 NP_003587.1 370 42188 T101 D I R C G E E T R V I P R I L
Chimpanzee Pan troglodytes XP_001172350 377 41866 T100 E V R C G E E T R I I P R V L
Rhesus Macaque Macaca mulatta XP_001086632 370 42168 T101 D I R C G E E T R V I P R I L
Dog Lupus familis XP_546906 370 42192 T101 D I R C G E E T R V I P R I L
Cat Felis silvestris
Mouse Mus musculus O70281 370 42114 T101 D I R C G E E T R V I P R I L
Rat Rattus norvegicus Q3KR92 370 42117 T101 D I R C G E E T R V I P R I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJI0 371 42023 T98 E V R C G E E T R I I P R V L
Frog Xenopus laevis NP_001085590 372 42191 T99 E V R C G E E T R V I P R I L
Zebra Danio Brachydanio rerio Q9PTE6 355 40179 T98 D V R C G E E T R V I P R I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYB7 499 58032 T102 D V R C G Q E T R V I P R I L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O77081 380 43295 T101 E V R C G E E T R V I P R I L
Sea Urchin Strong. purpuratus XP_001190618 798 90248 T91 D V R C G E E T R V I P R I L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.1 99.1 97.5 N.A. 96.4 96.2 N.A. N.A. 64.9 87.3 79.7 N.A. 44.6 N.A. 52.1 28.9
Protein Similarity: 100 77.4 99.7 99.7 N.A. 98.3 98.6 N.A. N.A. 79.7 93.5 88.6 N.A. 56.9 N.A. 69.2 36.5
P-Site Identity: 100 73.3 100 100 N.A. 100 100 N.A. N.A. 73.3 86.6 93.3 N.A. 86.6 N.A. 86.6 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 100 N.A. 100 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 34 0 0 0 0 92 100 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 42 0 0 0 0 0 0 0 17 100 0 0 84 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 100 0 0 0 0 0 100 0 0 0 100 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % T
% Val: 0 59 0 0 0 0 0 0 0 84 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _