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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPST1
All Species:
9.09
Human Site:
T49
Identified Species:
18.18
UniProt:
O60507
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60507
NP_003587.1
370
42188
T49
V
K
L
E
S
T
R
T
T
V
R
T
G
L
D
Chimpanzee
Pan troglodytes
XP_001172350
377
41866
E48
P
R
G
A
M
R
P
E
Q
E
E
L
V
M
V
Rhesus Macaque
Macaca mulatta
XP_001086632
370
42168
T49
V
K
L
E
S
T
R
T
T
V
R
T
G
L
D
Dog
Lupus familis
XP_546906
370
42192
T49
L
R
L
E
S
T
K
T
T
V
R
T
G
L
D
Cat
Felis silvestris
Mouse
Mus musculus
O70281
370
42114
A49
A
R
L
E
N
P
K
A
T
V
R
A
G
L
D
Rat
Rattus norvegicus
Q3KR92
370
42117
A49
A
R
L
E
N
P
K
A
T
V
R
T
G
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJI0
371
42023
E46
R
H
R
L
M
R
P
E
N
E
E
L
V
M
V
Frog
Xenopus laevis
NP_001085590
372
42191
A49
A
K
T
E
N
A
K
A
T
L
R
T
D
I
K
Zebra Danio
Brachydanio rerio
Q9PTE6
355
40179
L46
S
Q
P
L
L
S
S
L
H
A
T
L
R
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYB7
499
58032
V50
N
E
L
S
S
Q
M
V
R
V
E
K
Y
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77081
380
43295
E49
A
A
A
D
D
G
D
E
S
L
P
F
H
Q
L
Sea Urchin
Strong. purpuratus
XP_001190618
798
90248
P39
T
E
N
V
R
M
V
P
V
E
P
H
I
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.1
99.1
97.5
N.A.
96.4
96.2
N.A.
N.A.
64.9
87.3
79.7
N.A.
44.6
N.A.
52.1
28.9
Protein Similarity:
100
77.4
99.7
99.7
N.A.
98.3
98.6
N.A.
N.A.
79.7
93.5
88.6
N.A.
56.9
N.A.
69.2
36.5
P-Site Identity:
100
0
100
80
N.A.
53.3
60
N.A.
N.A.
0
33.3
0
N.A.
26.6
N.A.
0
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
73.3
80
N.A.
N.A.
6.6
60
13.3
N.A.
33.3
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
9
9
9
0
9
0
25
0
9
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
9
0
0
0
0
0
9
0
42
% D
% Glu:
0
17
0
50
0
0
0
25
0
25
25
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
9
0
0
9
0
0
0
0
0
0
42
0
9
% G
% His:
0
9
0
0
0
0
0
0
9
0
0
9
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% I
% Lys:
0
25
0
0
0
0
34
0
0
0
0
9
0
0
9
% K
% Leu:
9
0
50
17
9
0
0
9
0
17
0
25
0
59
9
% L
% Met:
0
0
0
0
17
9
9
0
0
0
0
0
0
17
0
% M
% Asn:
9
0
9
0
25
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
9
0
9
0
0
17
17
9
0
0
17
0
0
0
0
% P
% Gln:
0
9
0
0
0
9
0
0
9
0
0
0
0
9
0
% Q
% Arg:
9
34
9
0
9
17
17
0
9
0
50
0
9
0
0
% R
% Ser:
9
0
0
9
34
9
9
0
9
0
0
0
0
0
0
% S
% Thr:
9
0
9
0
0
25
0
25
50
0
9
42
0
9
9
% T
% Val:
17
0
0
9
0
0
9
9
9
50
0
0
17
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _