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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC40 All Species: 18.48
Human Site: S155 Identified Species: 33.89
UniProt: O60508 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60508 NP_056975.1 579 65521 S155 V S A K Y I G S V E E A E K N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088397 579 65473 S155 V S A K Y I G S V E E A E K N
Dog Lupus familis XP_532261 579 65433 S155 V S T K Y I G S V E E A E K N
Cat Felis silvestris
Mouse Mus musculus Q9DC48 579 65443 S155 V S A K Y I G S V E E A E K N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508497 591 67794 S167 V T T K Y I G S V E E A E K N
Chicken Gallus gallus
Frog Xenopus laevis Q6DE72 410 46731 D17 E L N R A I A D Y L R S N G Y
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023
Honey Bee Apis mellifera XP_396966 578 66029 K154 G K T I I G A K D A A E E S G
Nematode Worm Caenorhab. elegans Q9NDC9 404 45758 I11 S E R Q K E E I N R A I A E Y
Sea Urchin Strong. purpuratus XP_789449 577 65809 K153 G K H I V S N K E G T E P E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172528 573 65110 Q153 F N I P Q S E Q K R R K I E R
Baker's Yeast Sacchar. cerevisiae P40968 455 52029 T62 E L K R R R K T R K G D G P W
Red Bread Mold Neurospora crassa Q7RY30 453 49738 K59 Y E G L L E K K W T S V V R L
Conservation
Percent
Protein Identity: 100 N.A. 99.6 98.4 N.A. 98.7 N.A. N.A. 85.2 N.A. 20.2 N.A. N.A. 20.2 63.2 20.2 67.3
Protein Similarity: 100 N.A. 100 98.9 N.A. 99.4 N.A. N.A. 88.8 N.A. 34.5 N.A. N.A. 33.8 78.5 34.5 80.6
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 N.A. N.A. 86.6 N.A. 6.6 N.A. N.A. 0 6.6 0 0
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 N.A. N.A. 93.3 N.A. 20 N.A. N.A. 0 6.6 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 50.4 31.7 20.7
Protein Similarity: N.A. N.A. N.A. 66.3 48.7 37.3
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 13.3 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 24 0 8 0 16 0 0 8 16 39 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 8 0 0 8 0 0 0 % D
% Glu: 16 16 0 0 0 16 16 0 8 39 39 16 47 24 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 8 0 0 8 39 0 0 8 8 0 8 8 8 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 16 8 47 0 8 0 0 0 8 8 0 0 % I
% Lys: 0 16 8 39 8 0 16 24 8 8 0 8 0 39 0 % K
% Leu: 0 16 0 8 8 0 0 0 0 8 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 8 0 8 0 0 0 8 0 39 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 0 0 8 8 0 % P
% Gln: 0 0 0 8 8 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 16 8 8 0 0 8 16 16 0 0 8 8 % R
% Ser: 8 31 0 0 0 16 0 39 0 0 8 8 0 8 0 % S
% Thr: 0 8 24 0 0 0 0 8 0 8 8 0 0 0 0 % T
% Val: 39 0 0 0 8 0 0 0 39 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % W
% Tyr: 8 0 0 0 39 0 0 0 8 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _