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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC40
All Species:
32.42
Human Site:
S435
Identified Species:
59.44
UniProt:
O60508
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60508
NP_056975.1
579
65521
S435
D
E
N
R
R
F
V
S
T
S
D
D
K
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088397
579
65473
S435
D
E
N
R
R
F
V
S
T
S
D
D
K
S
L
Dog
Lupus familis
XP_532261
579
65433
S435
D
E
N
R
R
F
V
S
T
S
D
D
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC48
579
65443
S435
D
E
N
R
R
F
V
S
T
S
D
D
K
S
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508497
591
67794
S447
D
E
N
R
R
F
V
S
T
S
D
D
K
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DE72
410
46731
S289
I
S
W
A
P
E
S
S
Y
S
T
I
S
D
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
D240
L
K
T
L
I
D
D
D
N
P
P
V
S
F
V
Honey Bee
Apis mellifera
XP_396966
578
66029
T434
D
E
N
R
R
F
V
T
T
S
D
D
K
S
L
Nematode Worm
Caenorhab. elegans
Q9NDC9
404
45758
W283
H
A
V
E
C
V
E
W
A
P
D
T
A
Y
T
Sea Urchin
Strong. purpuratus
XP_789449
577
65809
T433
D
N
N
K
R
F
V
T
T
S
D
D
K
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172528
573
65110
T429
D
N
N
R
R
F
V
T
S
S
D
D
K
S
L
Baker's Yeast
Sacchar. cerevisiae
P40968
455
52029
T334
P
I
K
Q
I
S
D
T
A
Q
H
S
M
P
F
Red Bread Mold
Neurospora crassa
Q7RY30
453
49738
I332
T
G
S
R
D
K
S
I
R
L
W
D
A
R
G
Conservation
Percent
Protein Identity:
100
N.A.
99.6
98.4
N.A.
98.7
N.A.
N.A.
85.2
N.A.
20.2
N.A.
N.A.
20.2
63.2
20.2
67.3
Protein Similarity:
100
N.A.
100
98.9
N.A.
99.4
N.A.
N.A.
88.8
N.A.
34.5
N.A.
N.A.
33.8
78.5
34.5
80.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
100
N.A.
13.3
N.A.
N.A.
0
93.3
6.6
80
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
100
N.A.
13.3
N.A.
N.A.
13.3
100
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.4
31.7
20.7
Protein Similarity:
N.A.
N.A.
N.A.
66.3
48.7
37.3
P-Site Identity:
N.A.
N.A.
N.A.
80
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
16
0
0
0
16
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
0
0
0
8
8
16
8
0
0
70
70
0
8
0
% D
% Glu:
0
47
0
8
0
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
62
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
8
0
0
16
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
8
8
8
0
8
0
0
0
0
0
0
62
0
0
% K
% Leu:
8
0
0
8
0
0
0
0
0
8
0
0
0
0
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
16
62
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
8
0
0
0
0
16
8
0
0
8
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
62
62
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
0
8
8
0
0
8
16
47
8
70
0
8
16
62
0
% S
% Thr:
8
0
8
0
0
0
0
31
54
0
8
8
0
0
8
% T
% Val:
0
0
8
0
0
8
62
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _