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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC40 All Species: 30
Human Site: T371 Identified Species: 55
UniProt: O60508 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60508 NP_056975.1 579 65521 T371 G Q C I S R F T N R K V P Y C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088397 579 65473 T371 G Q C I S R F T N R K V P Y C
Dog Lupus familis XP_532261 579 65433 T371 G Q C I S R F T N R K V P Y C
Cat Felis silvestris
Mouse Mus musculus Q9DC48 579 65443 T371 G Q C I S R F T N R K V P Y C
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508497 591 67794 T383 G Q C I S R F T N R K V P Y C
Chicken Gallus gallus
Frog Xenopus laevis Q6DE72 410 46731 T229 Q T G Y C V K T F T G H R E W
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023 V180 S G S F D E S V R I W D V R T
Honey Bee Apis mellifera XP_396966 578 66029 T370 G A C I S R F T S R K I P Y C
Nematode Worm Caenorhab. elegans Q9NDC9 404 45758 G223 K Q W D I S T G Y C V Y T F R
Sea Urchin Strong. purpuratus XP_789449 577 65809 T369 G E C I E K F T S R K V P Y C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172528 573 65110 S365 G Q V I S T F S T G K I P Y V
Baker's Yeast Sacchar. cerevisiae P40968 455 52029 H274 L S N S K I L H Y D D R V S E
Red Bread Mold Neurospora crassa Q7RY30 453 49738 D272 D Y T S R L W D V T I T N P E
Conservation
Percent
Protein Identity: 100 N.A. 99.6 98.4 N.A. 98.7 N.A. N.A. 85.2 N.A. 20.2 N.A. N.A. 20.2 63.2 20.2 67.3
Protein Similarity: 100 N.A. 100 98.9 N.A. 99.4 N.A. N.A. 88.8 N.A. 34.5 N.A. N.A. 33.8 78.5 34.5 80.6
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 100 N.A. 6.6 N.A. N.A. 0 80 6.6 73.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 100 N.A. 6.6 N.A. N.A. 0 93.3 13.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 50.4 31.7 20.7
Protein Similarity: N.A. N.A. N.A. 66.3 48.7 37.3
P-Site Identity: N.A. N.A. N.A. 53.3 0 0
P-Site Similarity: N.A. N.A. N.A. 66.6 0 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 54 0 8 0 0 0 0 8 0 0 0 0 54 % C
% Asp: 8 0 0 8 8 0 0 8 0 8 8 8 0 0 0 % D
% Glu: 0 8 0 0 8 8 0 0 0 0 0 0 0 8 16 % E
% Phe: 0 0 0 8 0 0 62 0 8 0 0 0 0 8 0 % F
% Gly: 62 8 8 0 0 0 0 8 0 8 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 62 8 8 0 0 0 8 8 16 0 0 0 % I
% Lys: 8 0 0 0 8 8 8 0 0 0 62 0 0 0 0 % K
% Leu: 8 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 39 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 62 8 0 % P
% Gln: 8 54 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 47 0 0 8 54 0 8 8 8 8 % R
% Ser: 8 8 8 16 54 8 8 8 16 0 0 0 0 8 0 % S
% Thr: 0 8 8 0 0 8 8 62 8 16 0 8 8 0 8 % T
% Val: 0 0 8 0 0 8 0 8 8 0 8 47 16 0 8 % V
% Trp: 0 0 8 0 0 0 8 0 0 0 8 0 0 0 8 % W
% Tyr: 0 8 0 8 0 0 0 0 16 0 0 8 0 62 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _