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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC40 All Species: 17.58
Human Site: T68 Identified Species: 32.22
UniProt: O60508 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60508 NP_056975.1 579 65521 T68 A V K E D L E T G V H L D P A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088397 579 65473 T68 A V K E D L E T G V H L D P A
Dog Lupus familis XP_532261 579 65433 T68 A V K E D L E T G V H L D P A
Cat Felis silvestris
Mouse Mus musculus Q9DC48 579 65443 T68 A V K E D L E T G V H L D P A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508497 591 67794 T80 D F A E D V E T G V H L D P A
Chicken Gallus gallus
Frog Xenopus laevis Q6DE72 410 46731
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023
Honey Bee Apis mellifera XP_396966 578 66029 I69 T E L C I N Q I D S T I K E V
Nematode Worm Caenorhab. elegans Q9NDC9 404 45758
Sea Urchin Strong. purpuratus XP_789449 577 65809 Y68 S D Y G T N P Y Q P L D P S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172528 573 65110 H68 V V F Y N P T H D Q L W A P M
Baker's Yeast Sacchar. cerevisiae P40968 455 52029
Red Bread Mold Neurospora crassa Q7RY30 453 49738
Conservation
Percent
Protein Identity: 100 N.A. 99.6 98.4 N.A. 98.7 N.A. N.A. 85.2 N.A. 20.2 N.A. N.A. 20.2 63.2 20.2 67.3
Protein Similarity: 100 N.A. 100 98.9 N.A. 99.4 N.A. N.A. 88.8 N.A. 34.5 N.A. N.A. 33.8 78.5 34.5 80.6
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 73.3 N.A. 0 N.A. N.A. 0 0 0 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 80 N.A. 0 N.A. N.A. 0 13.3 0 6.6
Percent
Protein Identity: N.A. N.A. N.A. 50.4 31.7 20.7
Protein Similarity: N.A. N.A. N.A. 66.3 48.7 37.3
P-Site Identity: N.A. N.A. N.A. 13.3 0 0
P-Site Similarity: N.A. N.A. N.A. 20 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 0 8 0 0 0 0 0 0 0 0 0 8 0 39 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 39 0 0 0 16 0 0 8 39 0 0 % D
% Glu: 0 8 0 39 0 0 39 0 0 0 0 0 0 8 0 % E
% Phe: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 39 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 39 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 8 0 0 0 8 0 0 0 % I
% Lys: 0 0 31 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 8 0 0 31 0 0 0 0 16 39 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 8 16 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 8 0 0 8 0 0 8 47 0 % P
% Gln: 0 0 0 0 0 0 8 0 8 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % S
% Thr: 8 0 0 0 8 0 8 39 0 0 8 0 0 0 8 % T
% Val: 8 39 0 0 0 8 0 0 0 39 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 8 8 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _