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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC40
All Species:
25.76
Human Site:
Y199
Identified Species:
47.22
UniProt:
O60508
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60508
NP_056975.1
579
65521
Y199
F
L
G
P
W
A
K
Y
V
D
E
K
D
V
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088397
579
65473
Y199
F
L
G
P
W
A
K
Y
V
D
E
K
D
V
A
Dog
Lupus familis
XP_532261
579
65433
Y199
F
L
G
P
W
A
K
Y
V
D
E
K
D
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC48
579
65443
Y199
F
L
G
P
W
A
K
Y
V
D
E
K
D
V
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508497
591
67794
Y211
F
L
G
P
W
A
K
Y
V
D
E
K
D
V
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DE72
410
46731
L61
K
W
T
S
V
I
R
L
Q
K
K
V
M
E
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
P12
G
A
V
H
G
G
H
P
G
V
V
H
P
P
Q
Honey Bee
Apis mellifera
XP_396966
578
66029
Y198
F
L
G
P
W
G
G
Y
V
D
E
K
R
I
I
Nematode Worm
Caenorhab. elegans
Q9NDC9
404
45758
T55
I
L
E
K
K
W
T
T
V
L
R
L
Q
R
K
Sea Urchin
Strong. purpuratus
XP_789449
577
65809
Y197
F
E
G
P
W
G
K
Y
V
D
E
K
T
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172528
573
65110
R197
N
R
K
S
P
W
S
R
K
K
E
V
V
Q
G
Baker's Yeast
Sacchar. cerevisiae
P40968
455
52029
Q106
E
D
N
L
D
S
E
Q
I
E
V
E
E
V
S
Red Bread Mold
Neurospora crassa
Q7RY30
453
49738
R103
D
P
V
A
W
L
P
R
A
P
P
R
H
T
L
Conservation
Percent
Protein Identity:
100
N.A.
99.6
98.4
N.A.
98.7
N.A.
N.A.
85.2
N.A.
20.2
N.A.
N.A.
20.2
63.2
20.2
67.3
Protein Similarity:
100
N.A.
100
98.9
N.A.
99.4
N.A.
N.A.
88.8
N.A.
34.5
N.A.
N.A.
33.8
78.5
34.5
80.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
0
66.6
13.3
80
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
100
N.A.
13.3
N.A.
N.A.
0
73.3
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.4
31.7
20.7
Protein Similarity:
N.A.
N.A.
N.A.
66.3
48.7
37.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
53.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
39
0
0
8
0
0
0
0
0
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
0
0
0
0
54
0
0
39
0
0
% D
% Glu:
8
8
8
0
0
0
8
0
0
8
62
8
8
8
0
% E
% Phe:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
54
0
8
24
8
0
8
0
0
0
0
0
8
% G
% His:
0
0
0
8
0
0
8
0
0
0
0
8
8
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
8
0
0
0
0
8
8
% I
% Lys:
8
0
8
8
8
0
47
0
8
16
8
54
0
0
8
% K
% Leu:
0
54
0
8
0
8
0
8
0
8
0
8
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
54
8
0
8
8
0
8
8
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
0
0
8
8
8
% Q
% Arg:
0
8
0
0
0
0
8
16
0
0
8
8
8
8
0
% R
% Ser:
0
0
0
16
0
8
8
0
0
0
0
0
0
0
8
% S
% Thr:
0
0
8
0
0
0
8
8
0
0
0
0
8
8
0
% T
% Val:
0
0
16
0
8
0
0
0
62
8
16
16
8
54
0
% V
% Trp:
0
8
0
0
62
16
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _