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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC40
All Species:
24.55
Human Site:
Y275
Identified Species:
45
UniProt:
O60508
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60508
NP_056975.1
579
65521
Y275
T
M
P
P
E
K
C
Y
L
P
K
K
Q
I
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088397
579
65473
Y275
T
M
P
P
E
K
C
Y
L
P
K
K
Q
I
H
Dog
Lupus familis
XP_532261
579
65433
Y275
T
V
P
P
E
K
C
Y
L
P
K
K
Q
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC48
579
65443
Y275
S
V
P
P
E
K
C
Y
L
P
K
K
Q
I
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508497
591
67794
Y287
P
V
P
P
E
K
C
Y
L
P
K
K
Q
I
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DE72
410
46731
K133
A
S
E
D
A
T
I
K
V
W
D
Y
E
T
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
G84
A
V
K
F
S
P
N
G
E
W
L
A
S
S
S
Honey Bee
Apis mellifera
XP_396966
578
66029
F274
E
S
P
P
D
R
C
F
L
P
K
A
Q
I
H
Nematode Worm
Caenorhab. elegans
Q9NDC9
404
45758
D127
I
M
A
S
C
S
E
D
A
T
I
K
V
W
D
Sea Urchin
Strong. purpuratus
XP_789449
577
65809
Y273
E
L
P
P
E
K
C
Y
L
P
K
K
A
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172528
573
65110
Y269
K
A
N
N
D
H
C
Y
I
P
K
R
L
V
H
Baker's Yeast
Sacchar. cerevisiae
P40968
455
52029
I178
L
P
K
T
G
H
L
I
L
S
G
G
N
D
H
Red Bread Mold
Neurospora crassa
Q7RY30
453
49738
C176
G
N
T
L
L
A
S
C
S
S
D
L
T
I
K
Conservation
Percent
Protein Identity:
100
N.A.
99.6
98.4
N.A.
98.7
N.A.
N.A.
85.2
N.A.
20.2
N.A.
N.A.
20.2
63.2
20.2
67.3
Protein Similarity:
100
N.A.
100
98.9
N.A.
99.4
N.A.
N.A.
88.8
N.A.
34.5
N.A.
N.A.
33.8
78.5
34.5
80.6
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
N.A.
N.A.
86.6
N.A.
0
N.A.
N.A.
0
60
13.3
80
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
13.3
N.A.
N.A.
6.6
80
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.4
31.7
20.7
Protein Similarity:
N.A.
N.A.
N.A.
66.3
48.7
37.3
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
60
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
0
8
8
0
0
8
0
0
16
8
0
0
% A
% Cys:
0
0
0
0
8
0
62
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
16
0
0
8
0
0
16
0
0
8
8
% D
% Glu:
16
0
8
0
47
0
8
0
8
0
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
8
0
0
8
8
0
0
8
% G
% His:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
70
% H
% Ile:
8
0
0
0
0
0
8
8
8
0
8
0
0
62
0
% I
% Lys:
8
0
16
0
0
47
0
8
0
0
62
54
0
0
8
% K
% Leu:
8
8
0
8
8
0
8
0
62
0
8
8
8
0
0
% L
% Met:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
8
8
54
54
0
8
0
0
0
62
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
16
0
8
8
8
8
0
8
16
0
0
8
8
8
% S
% Thr:
24
0
8
8
0
8
0
0
0
8
0
0
8
8
0
% T
% Val:
0
31
0
0
0
0
0
0
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
16
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _