KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC40
All Species:
26.67
Human Site:
Y543
Identified Species:
48.89
UniProt:
O60508
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60508
NP_056975.1
579
65521
Y543
D
W
K
T
T
K
L
Y
S
R
F
K
A
H
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088397
579
65473
Y543
D
W
K
T
T
K
L
Y
S
R
F
K
A
H
D
Dog
Lupus familis
XP_532261
579
65433
Y543
D
W
K
T
T
K
L
Y
S
R
F
K
A
H
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC48
579
65443
Y543
D
W
K
T
T
K
L
Y
S
R
F
K
A
H
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508497
591
67794
Y555
D
W
K
T
T
K
L
Y
S
R
F
K
A
H
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DE72
410
46731
F382
T
L
N
A
H
E
H
F
V
T
S
L
D
F
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
C333
G
H
T
D
T
V
L
C
T
A
C
H
P
T
E
Honey Bee
Apis mellifera
XP_396966
578
66029
Y542
D
W
K
T
T
K
L
Y
K
K
W
K
A
H
D
Nematode Worm
Caenorhab. elegans
Q9NDC9
404
45758
F376
A
I
E
A
H
E
H
F
V
S
T
V
A
F
H
Sea Urchin
Strong. purpuratus
XP_789449
577
65809
Y541
D
W
K
S
T
K
L
Y
T
K
L
K
A
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172528
573
65110
F537
D
W
K
S
C
K
V
F
R
T
L
K
C
H
N
Baker's Yeast
Sacchar. cerevisiae
P40968
455
52029
K427
N
I
K
I
P
G
N
K
P
I
T
Q
V
D
W
Red Bread Mold
Neurospora crassa
Q7RY30
453
49738
G425
P
N
G
T
P
K
K
G
G
A
A
A
T
P
E
Conservation
Percent
Protein Identity:
100
N.A.
99.6
98.4
N.A.
98.7
N.A.
N.A.
85.2
N.A.
20.2
N.A.
N.A.
20.2
63.2
20.2
67.3
Protein Similarity:
100
N.A.
100
98.9
N.A.
99.4
N.A.
N.A.
88.8
N.A.
34.5
N.A.
N.A.
33.8
78.5
34.5
80.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
13.3
80
6.6
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
100
N.A.
13.3
N.A.
N.A.
26.6
93.3
26.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.4
31.7
20.7
Protein Similarity:
N.A.
N.A.
N.A.
66.3
48.7
37.3
P-Site Identity:
N.A.
N.A.
N.A.
40
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
0
0
0
0
16
8
8
62
0
0
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
8
0
8
0
0
% C
% Asp:
62
0
0
8
0
0
0
0
0
0
0
0
8
8
54
% D
% Glu:
0
0
8
0
0
16
0
0
0
0
0
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
24
0
0
39
0
0
16
0
% F
% Gly:
8
0
8
0
0
8
0
8
8
0
0
0
0
0
0
% G
% His:
0
8
0
0
16
0
16
0
0
0
0
8
0
62
16
% H
% Ile:
0
16
0
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
70
0
0
70
8
8
8
16
0
62
0
0
0
% K
% Leu:
0
8
0
0
0
0
62
0
0
0
16
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
16
0
0
0
8
0
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
39
0
0
0
0
0
% R
% Ser:
0
0
0
16
0
0
0
0
39
8
8
0
0
0
0
% S
% Thr:
8
0
8
54
62
0
0
0
16
16
16
0
8
8
0
% T
% Val:
0
0
0
0
0
8
8
0
16
0
0
8
8
0
0
% V
% Trp:
0
62
0
0
0
0
0
0
0
0
8
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _