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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GMDS All Species: 39.09
Human Site: Y179 Identified Species: 66.15
UniProt: O60547 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60547 NP_001491.1 372 41950 Y179 P F Y P R S P Y G A A K L Y A
Chimpanzee Pan troglodytes XP_518203 264 29387 V94 L T D S T C L V K I I N E V K
Rhesus Macaque Macaca mulatta XP_001089757 372 41939 Y179 P F Y P R S P Y G A A K L Y A
Dog Lupus familis XP_545311 382 43047 Y199 P F Y P R S P Y G A A K L Y A
Cat Felis silvestris
Mouse Mus musculus Q8K0C9 372 41966 Y179 P F Y P R S P Y G A A K L Y A
Rat Rattus norvegicus NP_001034695 372 42076 Y179 P F Y P R S P Y G A A K L Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510139 419 47462 Y226 P F Y P R S P Y G A A K L Y A
Chicken Gallus gallus XP_418977 573 61938 Y380 P F Y P R S P Y G A A K L Y A
Frog Xenopus laevis NP_001085613 369 41575 G177 F Y P R S P Y G A A K L Y A Y
Zebra Danio Brachydanio rerio NP_001095945 370 41741 Y177 P F Y P R S P Y G A A K L Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMW9 395 44765 Y202 P F Y P R S P Y A C A K M Y G
Honey Bee Apis mellifera XP_395164 356 40352 R178 F W I V I N Y R E A Y N M F A
Nematode Worm Caenorhab. elegans Q18801 399 44470 Y207 P F Y P R S P Y A V A K M Y G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SNY3 361 40832 K177 R S P Y A A S K C A A H W Y T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.4 99.4 76.6 N.A. 97 96.5 N.A. 82.5 61 88.4 83 N.A. 65.8 66.4 59.6 N.A.
Protein Similarity: 100 70.9 99.7 81.9 N.A. 98.3 97.8 N.A. 86.1 63.3 91.9 90.5 N.A. 77.9 81.9 72.9 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 100 6.6 100 N.A. 73.3 13.3 73.3 N.A.
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 100 100 13.3 100 N.A. 80 40 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 50.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 68 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 0 0 22 79 79 0 0 8 65 % A
% Cys: 0 0 0 0 0 8 0 0 8 8 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % E
% Phe: 15 72 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 8 58 0 0 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 8 0 8 72 0 0 8 % K
% Leu: 8 0 0 0 0 0 8 0 0 0 0 8 58 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 22 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 15 0 0 0 % N
% Pro: 72 0 15 72 0 8 72 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 8 72 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 8 8 72 8 0 0 0 0 0 0 0 0 % S
% Thr: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 8 % T
% Val: 0 0 0 8 0 0 0 8 0 8 0 0 0 8 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 8 72 8 0 0 15 72 0 0 8 0 8 79 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _