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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NMT2 All Species: 35.45
Human Site: S258 Identified Species: 52
UniProt: O60551 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60551 NP_004799.1 498 56980 S258 C V H K K L R S K R V A P V L
Chimpanzee Pan troglodytes XP_507670 503 58620 S263 C V H K K L R S K R V A P V L
Rhesus Macaque Macaca mulatta XP_001115168 496 56780 S256 C V H K K L R S K R V A P V L
Dog Lupus familis XP_537613 496 56755 S256 C V H K K L R S K R V A P V L
Cat Felis silvestris
Mouse Mus musculus O70311 529 60466 S289 C V H K K L R S K R V A P V L
Rat Rattus norvegicus Q8K1Q0 496 56842 S256 C V H K K L R S K R V A P V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508763 606 68956 L330 D L S N A E V L K E L Y T L L
Chicken Gallus gallus XP_418632 498 56792 S258 C V H K K L R S K R V A P V L
Frog Xenopus laevis NP_001086116 498 57144 S258 C V H K K L R S K R V A P V L
Zebra Danio Brachydanio rerio NP_001018316 487 55671 A247 C V H K K L R A K R V A P V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61613 472 53814 T244 P V L I R E I T R R V N L T G
Honey Bee Apis mellifera XP_624861 471 54938 T244 P V L I R E I T R R V N L Q G
Nematode Worm Caenorhab. elegans P46548 450 50870 V226 E I T R R V N V T G I F Q A A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LTR9 434 49780 E210 V T R R V H L E N I W Q A A Y
Baker's Yeast Sacchar. cerevisiae P14743 455 52819 E231 L N W K K L Y E V D F T G L P
Red Bread Mold Neurospora crassa Q7S3C8 569 64133 G299 C I H K K L R G K R L A P V L
Conservation
Percent
Protein Identity: 100 84.6 69.4 69.8 N.A. 90.1 70.6 N.A. 58.9 94.3 87.7 74 N.A. 56 58.6 49.7 N.A.
Protein Similarity: 100 87 80.1 80.9 N.A. 92.8 82.3 N.A. 65.5 96.9 94.1 83.5 N.A. 68 72.8 65.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 100 93.3 N.A. 20 20 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 100 100 100 N.A. 40 40 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 48.8 40.7 42
Protein Similarity: N.A. N.A. N.A. 63.4 57.8 57.2
P-Site Identity: N.A. N.A. N.A. 0 20 80
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 7 0 0 0 63 7 13 7 % A
% Cys: 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % D
% Glu: 7 0 0 0 0 19 0 13 0 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 7 0 7 0 0 7 0 13 % G
% His: 0 0 63 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 13 0 0 13 0 0 7 7 0 0 0 0 % I
% Lys: 0 0 0 69 69 0 0 0 69 0 0 0 0 0 0 % K
% Leu: 7 7 13 0 0 69 7 7 0 0 13 0 13 13 69 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 0 7 0 7 0 0 13 0 0 0 % N
% Pro: 13 0 0 0 0 0 0 0 0 0 0 0 63 0 7 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 7 7 7 0 % Q
% Arg: 0 0 7 13 19 0 63 0 13 75 0 0 0 0 0 % R
% Ser: 0 0 7 0 0 0 0 50 0 0 0 0 0 0 0 % S
% Thr: 0 7 7 0 0 0 0 13 7 0 0 7 7 7 0 % T
% Val: 7 69 0 0 7 7 7 7 7 0 69 0 0 63 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _