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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GREM1
All Species:
24.85
Human Site:
S76
Identified Species:
68.33
UniProt:
O60565
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60565
NP_037504.1
184
20697
S76
P
G
E
E
V
L
E
S
S
Q
E
A
L
H
V
Chimpanzee
Pan troglodytes
XP_523036
240
26508
S132
P
G
E
E
V
L
E
S
S
Q
E
A
L
H
V
Rhesus Macaque
Macaca mulatta
XP_001110846
267
30242
A144
F
M
F
R
K
S
P
A
S
Q
G
V
I
L
P
Dog
Lupus familis
XP_544600
184
20708
S76
P
G
E
E
V
L
E
S
S
Q
E
A
L
H
V
Cat
Felis silvestris
Mouse
Mus musculus
O70326
184
20691
S76
P
G
E
E
V
L
E
S
S
Q
E
A
L
H
V
Rat
Rattus norvegicus
O35793
184
20661
S76
P
G
E
E
V
L
E
S
S
Q
E
A
L
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519831
144
16367
S37
G
E
E
V
L
E
S
S
Q
E
A
L
H
V
T
Chicken
Gallus gallus
O73755
184
21148
S76
P
A
E
E
V
L
E
S
S
Q
E
A
L
H
I
Frog
Xenopus laevis
O73754
182
20356
S75
A
E
E
V
L
E
S
S
Q
E
A
L
H
V
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.6
23.6
99.4
N.A.
97.8
98.3
N.A.
58.1
83.6
82.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
76.6
35.2
99.4
N.A.
98.3
98.9
N.A.
66.3
90.2
89.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
13.3
86.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
26.6
93.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
0
0
12
0
0
23
67
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
23
89
67
0
23
67
0
0
23
67
0
0
0
0
% E
% Phe:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
56
0
0
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
23
67
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% I
% Lys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
23
67
0
0
0
0
0
23
67
12
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
23
78
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
12
23
89
78
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% T
% Val:
0
0
0
23
67
0
0
0
0
0
0
12
0
23
56
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _