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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLR5
All Species:
7.27
Human Site:
Y161
Identified Species:
16
UniProt:
O60602
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60602
NP_003259.2
858
97834
Y161
K
N
Q
I
R
S
L
Y
L
H
P
S
F
G
K
Chimpanzee
Pan troglodytes
NP_001123934
858
97884
Y161
K
N
Q
I
R
S
L
Y
L
H
P
S
F
G
K
Rhesus Macaque
Macaca mulatta
B3Y618
784
90053
Y136
L
N
L
L
G
N
P
Y
K
T
L
G
E
T
S
Dog
Lupus familis
XP_545722
1093
119004
E396
K
N
Q
I
G
S
L
E
L
H
A
S
F
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLF7
859
97608
R162
G
N
Q
I
H
S
L
R
L
H
S
S
F
R
E
Rat
Rattus norvegicus
Q9QX05
835
96053
L140
V
E
T
K
M
T
S
L
E
G
F
H
I
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512233
858
98473
P161
T
N
R
I
Q
S
L
P
L
H
A
S
F
R
E
Chicken
Gallus gallus
Q9DGB6
781
89077
G133
L
Q
H
L
R
I
Q
G
N
S
Y
S
D
L
G
Frog
Xenopus laevis
NP_001088449
878
100868
K175
S
N
E
I
A
Y
L
K
P
N
P
L
F
Y
H
Zebra Danio
Brachydanio rerio
NP_001124067
875
100402
Q162
D
N
N
I
Q
K
I
Q
P
A
S
F
F
L
N
Tiger Blowfish
Takifugu rubipres
NP_001027751
965
111466
S195
F
N
R
L
T
S
L
S
H
S
N
V
S
L
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
22
51.7
N.A.
72.4
24.8
N.A.
63.2
24.1
46.7
38
25.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
43
62.3
N.A.
81.8
44.1
N.A.
78
41.9
63.7
55.6
43.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
66.6
N.A.
60
6.6
N.A.
53.3
13.3
33.3
20
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
73.3
N.A.
66.6
20
N.A.
73.3
20
46.6
33.3
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
10
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
10
10
0
0
0
0
10
10
0
0
0
10
0
28
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
10
10
64
0
0
% F
% Gly:
10
0
0
0
19
0
0
10
0
10
0
10
0
28
10
% G
% His:
0
0
10
0
10
0
0
0
10
46
0
10
0
0
10
% H
% Ile:
0
0
0
64
0
10
10
0
0
0
0
0
10
0
0
% I
% Lys:
28
0
0
10
0
10
0
10
10
0
0
0
0
0
19
% K
% Leu:
19
0
10
28
0
0
64
10
46
0
10
10
0
28
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
82
10
0
0
10
0
0
10
10
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
10
10
19
0
28
0
0
0
10
% P
% Gln:
0
10
37
0
19
0
10
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
19
0
28
0
0
10
0
0
0
0
0
28
0
% R
% Ser:
10
0
0
0
0
55
10
10
0
19
19
55
10
0
10
% S
% Thr:
10
0
10
0
10
10
0
0
0
10
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
28
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _