KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLR2
All Species:
27.27
Human Site:
T699
Identified Species:
85.71
UniProt:
O60603
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60603
NP_003255.2
784
89838
T699
S
I
E
K
S
H
K
T
V
F
V
L
S
E
N
Chimpanzee
Pan troglodytes
B3Y613
784
89806
T699
S
I
E
K
S
H
K
T
V
F
V
L
S
E
N
Rhesus Macaque
Macaca mulatta
B3Y618
784
90053
T699
S
I
E
K
S
H
K
T
V
F
V
L
S
E
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUN7
784
89431
T699
S
I
E
K
S
H
K
T
V
F
V
L
S
E
N
Rat
Rattus norvegicus
Q9QX05
835
96053
V731
G
F
H
K
S
R
K
V
I
V
V
V
S
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512072
842
96115
T705
S
I
E
K
S
H
K
T
L
F
V
L
S
E
N
Chicken
Gallus gallus
Q9DGB6
781
89077
T696
S
I
E
K
S
H
K
T
L
F
V
L
S
E
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997977
788
89978
T700
S
I
E
K
S
Y
R
T
L
F
V
L
S
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.7
N.A.
N.A.
70.9
24.7
N.A.
56.5
53.3
N.A.
41.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
97.9
N.A.
N.A.
83.9
43.5
N.A.
71.6
70.9
N.A.
60.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
100
33.3
N.A.
93.3
86.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
53.3
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
88
0
0
0
0
0
0
0
0
0
0
88
0
% E
% Phe:
0
13
0
0
0
0
0
0
0
88
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
13
0
0
75
0
0
0
0
0
0
0
0
38
% H
% Ile:
0
88
0
0
0
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
0
0
0
100
0
0
88
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
38
0
0
88
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
63
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
13
13
0
0
0
0
0
0
13
0
% R
% Ser:
88
0
0
0
100
0
0
0
0
0
0
0
100
0
0
% S
% Thr:
0
0
0
0
0
0
0
88
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
13
50
13
100
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _