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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GFRA3 All Species: 13.03
Human Site: S353 Identified Species: 40.95
UniProt: O60609 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60609 NP_001487.2 400 44511 S353 A A K M R F H S Q L F S Q D W
Chimpanzee Pan troglodytes XP_517954 400 44509 S353 A A K M R F H S Q L F S Q D W
Rhesus Macaque Macaca mulatta XP_001112630 405 45108 S358 A A K M R F H S Q L F Y Q D W
Dog Lupus familis XP_538648 399 44370 S352 A A K M R F H S Q L F S Q D G
Cat Felis silvestris
Mouse Mus musculus O35118 397 44289 R350 A A K M R F H R Q L F S Q D W
Rat Rattus norvegicus Q62997 468 51631 D350 Q A F G N G S D V T M W Q P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O13157 465 51891 D358 Q A F G N G T D V N L S P K N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684588 484 54296 P376 D N M G S S T P R P V E G T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96 80.5 N.A. 77 31.2 N.A. N.A. 30.5 N.A. 29.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 97 86.5 N.A. 85.2 44.4 N.A. N.A. 44.7 N.A. 42.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 13.3 N.A. N.A. 13.3 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 13.3 N.A. N.A. 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 63 88 0 0 0 0 0 0 0 0 0 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 0 0 0 25 0 0 0 0 0 63 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % E
% Phe: 0 0 25 0 0 63 0 0 0 0 63 0 0 0 0 % F
% Gly: 0 0 0 38 0 25 0 0 0 0 0 0 13 0 13 % G
% His: 0 0 0 0 0 0 63 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 63 0 0 0 0 0 0 0 0 0 0 13 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 63 13 0 0 0 0 % L
% Met: 0 0 13 63 0 0 0 0 0 0 13 0 0 0 0 % M
% Asn: 0 13 0 0 25 0 0 0 0 13 0 0 0 0 13 % N
% Pro: 0 0 0 0 0 0 0 13 0 13 0 0 13 13 13 % P
% Gln: 25 0 0 0 0 0 0 0 63 0 0 0 75 0 0 % Q
% Arg: 0 0 0 0 63 0 0 13 13 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 13 13 13 50 0 0 0 63 0 0 0 % S
% Thr: 0 0 0 0 0 0 25 0 0 13 0 0 0 13 0 % T
% Val: 0 0 0 0 0 0 0 0 25 0 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 50 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _