KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSPAN2
All Species:
24.55
Human Site:
S46
Identified Species:
54
UniProt:
O60636
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60636
NP_005716.2
221
24148
S46
G
G
A
I
K
E
L
S
S
E
D
K
S
P
E
Chimpanzee
Pan troglodytes
XP_513675
346
37426
S171
G
G
A
I
K
E
L
S
S
E
D
K
S
P
E
Rhesus Macaque
Macaca mulatta
XP_001102665
228
25379
Q47
Q
T
K
S
I
F
E
Q
E
T
N
N
N
N
S
Dog
Lupus familis
XP_848759
221
24186
S46
G
G
T
M
K
G
F
S
S
E
D
K
S
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q922J6
221
24163
S46
G
G
T
M
K
D
L
S
S
E
D
K
S
P
E
Rat
Rattus norvegicus
Q9JJW1
221
24171
S46
G
G
T
I
K
D
L
S
S
E
E
K
S
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506057
265
29263
S90
G
G
V
V
K
D
L
S
S
G
D
K
S
P
E
Chicken
Gallus gallus
Q5ZIF5
305
35238
T46
L
N
N
V
L
T
L
T
A
E
T
R
V
E
E
Frog
Xenopus laevis
Q6GQF5
268
29872
A57
K
H
A
E
A
A
M
A
C
L
A
V
D
P
A
Zebra Danio
Brachydanio rerio
Q6GMK6
239
26765
S40
W
L
S
V
S
Q
G
S
F
A
T
F
S
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140831
236
25886
L49
T
S
L
L
Y
L
E
L
G
D
K
P
A
P
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.8
49.1
95
N.A.
93.6
94.5
N.A.
63.7
22.2
23.5
29.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.8
63.5
96.8
N.A.
96.8
98.1
N.A.
72.4
39.6
44.4
47.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
73.3
N.A.
80
80
N.A.
73.3
20
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
80
N.A.
93.3
93.3
N.A.
86.6
46.6
26.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
42.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
57.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
28
0
10
10
0
10
10
10
10
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
28
0
0
0
10
46
0
10
0
0
% D
% Glu:
0
0
0
10
0
19
19
0
10
55
10
0
0
10
64
% E
% Phe:
0
0
0
0
0
10
10
0
10
0
0
10
0
0
0
% F
% Gly:
55
55
0
0
0
10
10
0
10
10
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
28
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
10
0
55
0
0
0
0
0
10
55
0
0
0
% K
% Leu:
10
10
10
10
10
10
55
10
0
10
0
0
0
0
0
% L
% Met:
0
0
0
19
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
10
10
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
82
0
% P
% Gln:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
10
10
10
10
0
0
64
55
0
0
0
64
0
28
% S
% Thr:
10
10
28
0
0
10
0
10
0
10
19
0
0
0
0
% T
% Val:
0
0
10
28
0
0
0
0
0
0
0
10
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _