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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSPAN2
All Species:
21.52
Human Site:
T141
Identified Species:
47.33
UniProt:
O60636
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60636
NP_005716.2
221
24148
T141
D
R
G
K
G
N
G
T
L
I
T
F
H
S
T
Chimpanzee
Pan troglodytes
XP_513675
346
37426
T266
D
R
G
K
G
N
G
T
L
I
T
F
H
S
T
Rhesus Macaque
Macaca mulatta
XP_001102665
228
25379
T142
K
D
E
P
Q
R
E
T
L
K
A
I
H
Y
A
Dog
Lupus familis
XP_848759
221
24186
T141
D
K
E
R
G
N
G
T
L
I
T
F
H
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q922J6
221
24163
T141
D
R
A
R
G
N
G
T
L
I
T
F
H
S
A
Rat
Rattus norvegicus
Q9JJW1
221
24171
T141
D
R
G
R
G
N
G
T
L
I
T
F
H
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506057
265
29263
T185
D
E
G
K
G
N
Q
T
L
I
A
F
H
S
S
Chicken
Gallus gallus
Q5ZIF5
305
35238
P178
M
T
E
M
D
W
P
P
D
S
C
C
V
R
E
Frog
Xenopus laevis
Q6GQF5
268
29872
Q166
I
S
Y
K
D
W
S
Q
N
M
Y
F
N
C
S
Zebra Danio
Brachydanio rerio
Q6GMK6
239
26765
A137
N
N
V
G
L
R
N
A
W
N
I
I
Q
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140831
236
25886
V146
D
A
N
N
A
K
A
V
V
K
T
F
H
E
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.8
49.1
95
N.A.
93.6
94.5
N.A.
63.7
22.2
23.5
29.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.8
63.5
96.8
N.A.
96.8
98.1
N.A.
72.4
39.6
44.4
47.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
80
N.A.
80
86.6
N.A.
73.3
0
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
86.6
93.3
N.A.
80
0
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
42.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
57.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
10
10
0
0
19
0
0
10
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% C
% Asp:
64
10
0
0
19
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
28
0
0
0
10
0
0
0
0
0
0
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% F
% Gly:
0
0
37
10
55
0
46
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
55
10
19
0
0
0
% I
% Lys:
10
10
0
37
0
10
0
0
0
19
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
64
0
0
0
0
0
0
% L
% Met:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
10
10
10
0
55
10
0
10
10
0
0
10
0
0
% N
% Pro:
0
0
0
10
0
0
10
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
10
10
0
0
0
0
10
0
0
% Q
% Arg:
0
37
0
28
0
19
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
0
0
0
0
10
0
0
10
0
0
0
55
19
% S
% Thr:
0
10
0
0
0
0
0
64
0
0
55
0
0
0
37
% T
% Val:
0
0
10
0
0
0
0
10
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
19
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _