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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSPAN2 All Species: 21.21
Human Site: T144 Identified Species: 46.67
UniProt: O60636 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60636 NP_005716.2 221 24148 T144 K G N G T L I T F H S T F Q C
Chimpanzee Pan troglodytes XP_513675 346 37426 T269 K G N G T L I T F H S T F Q C
Rhesus Macaque Macaca mulatta XP_001102665 228 25379 A145 P Q R E T L K A I H Y A L D C
Dog Lupus familis XP_848759 221 24186 T144 R G N G T L I T F H S T F Q C
Cat Felis silvestris
Mouse Mus musculus Q922J6 221 24163 T144 R G N G T L I T F H S A F Q C
Rat Rattus norvegicus Q9JJW1 221 24171 T144 R G N G T L I T F H S A F Q C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506057 265 29263 A188 K G N Q T L I A F H S S L Q C
Chicken Gallus gallus Q5ZIF5 305 35238 C181 M D W P P D S C C V R E F P G
Frog Xenopus laevis Q6GQF5 268 29872 Y169 K D W S Q N M Y F N C S S E N
Zebra Danio Brachydanio rerio Q6GMK6 239 26765 I140 G L R N A W N I I Q A E W Q C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001140831 236 25886 T149 N A K A V V K T F H E T L N C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.8 49.1 95 N.A. 93.6 94.5 N.A. 63.7 22.2 23.5 29.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.8 63.5 96.8 N.A. 96.8 98.1 N.A. 72.4 39.6 44.4 47.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 26.6 93.3 N.A. 86.6 86.6 N.A. 73.3 6.6 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 93.3 93.3 N.A. 80 6.6 40 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 42.3 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 57.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 40 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 10 0 0 19 0 0 10 28 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 10 0 10 0 0 0 82 % C
% Asp: 0 19 0 0 0 10 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 10 19 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 73 0 0 0 55 0 0 % F
% Gly: 10 55 0 46 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 73 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 55 10 19 0 0 0 0 0 0 % I
% Lys: 37 0 10 0 0 0 19 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 64 0 0 0 0 0 0 28 0 0 % L
% Met: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 55 10 0 10 10 0 0 10 0 0 0 10 10 % N
% Pro: 10 0 0 10 10 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 10 0 10 10 0 0 0 0 10 0 0 0 64 0 % Q
% Arg: 28 0 19 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 10 0 0 0 55 19 10 0 0 % S
% Thr: 0 0 0 0 64 0 0 55 0 0 0 37 0 0 0 % T
% Val: 0 0 0 0 10 10 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 19 0 0 10 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _