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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSPAN3
All Species:
15.45
Human Site:
T125
Identified Species:
34
UniProt:
O60637
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60637
NP_005715.1
253
28018
T125
S
I
Q
K
V
Y
K
T
Y
N
G
T
N
P
D
Chimpanzee
Pan troglodytes
Q7YQL0
244
26954
T125
T
Y
T
D
A
M
Q
T
Y
N
G
N
D
E
R
Rhesus Macaque
Macaca mulatta
XP_001105998
253
27972
T125
S
I
Q
K
V
Y
K
T
Y
N
G
T
S
P
D
Dog
Lupus familis
XP_544788
424
45925
T296
S
I
Q
K
V
Y
K
T
Y
N
G
T
N
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY33
253
28030
T125
S
I
Q
K
V
Y
K
T
Y
N
G
T
N
S
D
Rat
Rattus norvegicus
P28648
238
25680
N125
S
F
Q
K
Q
M
Q
N
Y
L
T
D
N
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506336
253
28051
A125
S
I
E
K
V
Y
R
A
Y
N
G
T
S
P
D
Chicken
Gallus gallus
XP_001232465
253
28089
G125
S
I
Q
K
V
Y
N
G
Y
N
G
T
N
P
D
Frog
Xenopus laevis
Q6GQF5
268
29872
H135
I
I
S
N
A
I
E
H
Y
R
D
D
L
D
L
Zebra Danio
Brachydanio rerio
Q5RH71
281
31706
D138
A
I
K
H
Y
R
D
D
L
D
L
Q
N
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787025
263
29509
M128
D
N
G
L
N
N
T
M
K
H
Y
N
E
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.5
99.5
58
N.A.
97.2
32
N.A.
93.6
90.9
25.7
24.2
N.A.
N.A.
N.A.
N.A.
31.1
Protein Similarity:
100
51.7
100
59.4
N.A.
98.4
50.9
N.A.
97.2
94.4
44.7
45.9
N.A.
N.A.
N.A.
N.A.
51.7
P-Site Identity:
100
26.6
93.3
100
N.A.
93.3
33.3
N.A.
73.3
86.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
46.6
100
100
N.A.
93.3
40
N.A.
93.3
86.6
20
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
19
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
10
10
0
10
10
19
10
10
55
% D
% Glu:
0
0
10
0
0
0
10
0
0
0
0
0
10
10
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
0
64
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
0
% H
% Ile:
10
73
0
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
10
64
0
0
37
0
10
0
0
0
0
19
0
% K
% Leu:
0
0
0
10
0
0
0
0
10
10
10
0
10
10
10
% L
% Met:
0
0
0
0
0
19
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
10
10
10
0
64
0
19
55
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% P
% Gln:
0
0
55
0
10
0
19
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
10
% R
% Ser:
64
0
10
0
0
0
0
0
0
0
0
0
19
10
0
% S
% Thr:
10
0
10
0
0
0
10
46
0
0
10
55
0
0
10
% T
% Val:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
55
0
0
82
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _