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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSPAN3
All Species:
24.85
Human Site:
Y140
Identified Species:
54.67
UniProt:
O60637
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60637
NP_005715.1
253
28018
Y140
A
A
S
R
A
I
D
Y
V
Q
R
Q
L
H
C
Chimpanzee
Pan troglodytes
Q7YQL0
244
26954
Q140
S
R
A
V
D
H
V
Q
R
S
L
S
C
C
G
Rhesus Macaque
Macaca mulatta
XP_001105998
253
27972
Y140
A
A
S
R
A
I
D
Y
V
Q
R
Q
L
H
C
Dog
Lupus familis
XP_544788
424
45925
Y311
A
A
S
R
A
I
D
Y
V
Q
R
Q
L
H
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY33
253
28030
Y140
A
A
S
R
A
I
D
Y
V
Q
R
Q
L
H
C
Rat
Rattus norvegicus
P28648
238
25680
Q140
A
T
I
L
D
K
L
Q
K
E
N
K
C
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506336
253
28051
Y140
A
A
S
R
A
I
D
Y
V
Q
R
Q
L
R
C
Chicken
Gallus gallus
XP_001232465
253
28089
Y140
A
A
S
R
A
I
D
Y
V
Q
R
Q
L
R
C
Frog
Xenopus laevis
Q6GQF5
268
29872
Q150
Q
N
L
I
D
F
G
Q
K
E
F
S
C
C
G
Zebra Danio
Brachydanio rerio
Q5RH71
281
31706
N153
D
Y
G
Q
K
Q
F
N
C
C
G
G
I
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787025
263
29509
Y143
N
Y
Q
R
S
M
D
Y
V
Q
G
H
L
D
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.5
99.5
58
N.A.
97.2
32
N.A.
93.6
90.9
25.7
24.2
N.A.
N.A.
N.A.
N.A.
31.1
Protein Similarity:
100
51.7
100
59.4
N.A.
98.4
50.9
N.A.
97.2
94.4
44.7
45.9
N.A.
N.A.
N.A.
N.A.
51.7
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
93.3
93.3
0
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
20
N.A.
93.3
93.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
55
10
0
55
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
28
28
64
% C
% Asp:
10
0
0
0
28
0
64
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
10
% F
% Gly:
0
0
10
0
0
0
10
0
0
0
19
10
0
0
28
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
10
0
37
0
% H
% Ile:
0
0
10
10
0
55
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
10
10
0
0
19
0
0
10
0
0
0
% K
% Leu:
0
0
10
10
0
0
10
0
0
0
10
0
64
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
10
0
10
0
28
0
64
0
55
0
0
0
% Q
% Arg:
0
10
0
64
0
0
0
0
10
0
55
0
0
19
0
% R
% Ser:
10
0
55
0
10
0
0
0
0
10
0
19
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
10
0
64
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _