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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC3
All Species:
43.33
Human Site:
Y617
Identified Species:
79.44
UniProt:
O60645
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60645
NP_009208.2
756
86845
Y617
H
R
R
V
V
V
E
Y
L
R
A
V
M
Q
K
Chimpanzee
Pan troglodytes
XP_517603
745
85433
Y606
H
R
R
V
V
V
E
Y
L
R
A
V
M
Q
K
Rhesus Macaque
Macaca mulatta
XP_001094786
745
85541
Y606
H
R
R
V
V
V
E
Y
L
R
A
V
M
Q
K
Dog
Lupus familis
XP_848639
745
85558
Y606
Q
R
R
V
V
L
E
Y
L
R
A
V
M
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6KAR6
755
86436
Y616
H
R
R
V
V
V
E
Y
L
R
A
V
M
Q
K
Rat
Rattus norvegicus
Q62825
755
86478
Y616
H
R
R
V
V
V
E
Y
L
R
A
V
M
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514081
758
87572
Y620
H
R
R
V
V
V
E
Y
I
Q
A
I
M
Q
K
Chicken
Gallus gallus
NP_001006384
745
86251
Y606
H
R
R
V
V
V
E
Y
I
R
A
I
M
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2AV37
780
89063
Y636
Q
W
L
T
V
V
E
Y
V
R
A
V
M
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8K2
738
86645
Y605
Q
K
L
L
A
K
R
Y
I
R
A
L
L
S
K
Honey Bee
Apis mellifera
XP_395502
748
87222
Y608
Q
N
L
I
A
K
R
Y
I
S
A
M
L
Q
R
Nematode Worm
Caenorhab. elegans
Q19262
796
90635
Y636
Q
F
R
I
V
S
E
Y
L
K
A
I
E
T
K
Sea Urchin
Strong. purpuratus
XP_001202415
725
84963
S590
D
M
L
E
R
L
F
S
H
L
K
R
S
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
97.8
92.4
N.A.
95.6
94.3
N.A.
86.9
84.6
N.A.
33.5
N.A.
38.2
38.3
31.6
33.7
Protein Similarity:
100
98.1
98.1
96.1
N.A.
97.2
96.9
N.A.
93.1
90.7
N.A.
57.9
N.A.
58.5
59.6
56
52.1
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
80
80
N.A.
66.6
N.A.
26.6
20
46.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
93.3
N.A.
73.3
N.A.
60
53.3
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
0
0
0
0
93
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
0
0
77
0
0
0
0
0
8
8
0
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
54
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
0
0
31
0
0
24
0
0
0
% I
% Lys:
0
8
0
0
0
16
0
0
0
8
8
0
0
0
85
% K
% Leu:
0
0
31
8
0
16
0
0
54
8
0
8
16
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
70
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
39
0
0
0
0
0
0
0
0
8
0
0
0
70
0
% Q
% Arg:
0
62
70
0
8
0
16
0
0
70
0
8
0
0
8
% R
% Ser:
0
0
0
0
0
8
0
8
0
8
0
0
8
8
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
62
77
62
0
0
8
0
0
54
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _