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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC3
All Species:
42.42
Human Site:
Y696
Identified Species:
77.78
UniProt:
O60645
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60645
NP_009208.2
756
86845
Y696
V
S
T
L
V
S
K
Y
P
D
I
R
D
D
H
Chimpanzee
Pan troglodytes
XP_517603
745
85433
Y685
V
S
T
L
V
S
K
Y
P
D
I
R
D
D
H
Rhesus Macaque
Macaca mulatta
XP_001094786
745
85541
Y685
V
S
T
L
V
S
K
Y
P
D
I
R
D
D
H
Dog
Lupus familis
XP_848639
745
85558
Y685
V
S
T
L
V
S
K
Y
P
D
I
R
D
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6KAR6
755
86436
Y695
V
S
T
L
V
S
K
Y
P
D
I
R
D
D
H
Rat
Rattus norvegicus
Q62825
755
86478
Y695
V
S
T
L
V
S
K
Y
P
D
I
R
D
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514081
758
87572
Y699
V
S
T
L
V
S
K
Y
P
D
I
R
D
D
H
Chicken
Gallus gallus
NP_001006384
745
86251
Y685
V
S
T
L
V
S
K
Y
P
D
I
R
D
D
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2AV37
780
89063
Y715
I
S
G
L
L
S
K
Y
P
D
I
S
E
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8K2
738
86645
Y681
L
H
T
L
L
G
S
Y
P
S
L
N
E
D
H
Honey Bee
Apis mellifera
XP_395502
748
87222
Y686
L
H
S
L
V
E
K
Y
P
D
M
T
E
D
H
Nematode Worm
Caenorhab. elegans
Q19262
796
90635
F717
A
T
S
F
A
R
K
F
P
N
C
P
A
E
L
Sea Urchin
Strong. purpuratus
XP_001202415
725
84963
I667
T
S
M
L
S
L
E
I
S
T
L
V
H
R
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
97.8
92.4
N.A.
95.6
94.3
N.A.
86.9
84.6
N.A.
33.5
N.A.
38.2
38.3
31.6
33.7
Protein Similarity:
100
98.1
98.1
96.1
N.A.
97.2
96.9
N.A.
93.1
90.7
N.A.
57.9
N.A.
58.5
59.6
56
52.1
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
100
100
N.A.
60
N.A.
40
53.3
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
86.6
N.A.
66.6
80
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
77
0
0
62
70
0
% D
% Glu:
0
0
0
0
0
8
8
0
0
0
0
0
24
24
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
16
0
0
0
0
0
0
0
0
0
0
8
0
85
% H
% Ile:
8
0
0
0
0
0
0
8
0
0
70
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
85
0
0
0
0
0
0
0
0
% K
% Leu:
16
0
0
93
16
8
0
0
0
0
16
0
0
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
93
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
62
0
8
0
% R
% Ser:
0
77
16
0
8
70
8
0
8
8
0
8
0
0
0
% S
% Thr:
8
8
70
0
0
0
0
0
0
8
0
8
0
0
0
% T
% Val:
62
0
0
0
70
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _