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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LMX1B
All Species:
18.18
Human Site:
S157
Identified Species:
33.33
UniProt:
O60663
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60663
NP_002307.1
379
42409
S157
K
D
L
L
S
S
V
S
P
D
E
S
D
S
V
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
L141
T
T
G
S
D
P
S
L
S
P
D
S
Q
D
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537841
487
52979
S265
K
D
L
L
S
S
V
S
P
D
E
S
D
S
V
Cat
Felis silvestris
Mouse
Mus musculus
O88609
372
41550
S157
K
D
L
L
S
S
V
S
P
D
E
S
D
S
V
Rat
Rattus norvegicus
P63007
406
44762
L141
T
T
G
S
D
P
S
L
S
P
D
S
Q
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508297
558
60762
S349
K
D
L
L
S
S
V
S
P
D
E
S
D
S
V
Chicken
Gallus gallus
P53413
377
42546
V156
E
K
D
L
L
S
S
V
S
P
D
D
S
D
S
Frog
Xenopus laevis
P37137
402
44941
L141
S
S
C
T
D
R
S
L
S
P
D
I
Q
D
P
Zebra Danio
Brachydanio rerio
Q90476
405
45135
L140
T
A
C
S
D
P
S
L
S
P
D
S
Q
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
S70
K
N
F
G
A
K
C
S
K
C
C
R
G
I
S
Honey Bee
Apis mellifera
XP_001120677
404
44944
K176
R
D
Y
E
H
E
F
K
L
L
N
Y
H
D
F
Nematode Worm
Caenorhab. elegans
P20271
351
40037
S141
Q
C
F
I
C
K
R
S
L
E
T
G
E
E
F
Sea Urchin
Strong. purpuratus
XP_790548
391
43786
T177
K
R
P
R
T
I
L
T
T
S
Q
R
R
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.7
N.A.
76.5
N.A.
97.8
33.7
N.A.
40.8
92.8
34
34
N.A.
32.7
38.8
29.8
32.7
Protein Similarity:
100
48.2
N.A.
77.4
N.A.
97.8
48.2
N.A.
45.1
96
50.2
50.3
N.A.
45.9
55.2
46.7
46.2
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
6.6
N.A.
100
13.3
0
6.6
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
13.3
N.A.
100
26.6
6.6
13.3
N.A.
26.6
13.3
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
8
16
0
8
0
8
0
0
8
8
0
0
0
0
% C
% Asp:
0
39
8
0
31
0
0
0
0
31
39
8
31
47
0
% D
% Glu:
8
0
0
8
0
8
0
0
0
8
31
0
8
8
0
% E
% Phe:
0
0
16
0
0
0
8
0
0
0
0
0
0
0
24
% F
% Gly:
0
0
16
8
0
0
0
0
0
0
0
8
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
0
8
0
8
0
% I
% Lys:
47
8
0
0
0
16
0
8
8
0
0
0
0
0
0
% K
% Leu:
0
0
31
39
8
0
8
31
16
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
24
0
0
31
39
0
0
0
0
24
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
8
0
31
0
8
% Q
% Arg:
8
8
0
8
0
8
8
0
0
0
0
16
8
0
0
% R
% Ser:
8
8
0
24
31
39
39
47
39
8
0
54
8
31
16
% S
% Thr:
24
16
0
8
8
0
0
8
8
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
31
8
0
0
0
0
0
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _