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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC16A7
All Species:
9.7
Human Site:
S218
Identified Species:
23.7
UniProt:
O60669
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60669
NP_004722
478
52186
S218
T
G
K
T
E
D
D
S
S
P
K
K
I
K
T
Chimpanzee
Pan troglodytes
XP_001154930
500
54002
G218
K
A
S
L
E
K
A
G
K
S
G
V
K
K
D
Rhesus Macaque
Macaca mulatta
XP_001116628
478
52163
S218
T
V
T
T
E
D
D
S
G
Q
K
K
I
K
P
Dog
Lupus familis
XP_538259
483
53106
D217
I
G
I
R
V
D
D
D
S
D
V
T
K
R
L
Cat
Felis silvestris
Mouse
Mus musculus
O70451
484
52585
T219
V
G
S
R
H
D
S
T
L
K
K
A
S
K
V
Rat
Rattus norvegicus
Q63344
489
53039
S224
V
G
S
R
Q
D
S
S
T
K
R
L
S
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507090
482
52573
S218
V
E
N
G
A
G
N
S
S
L
L
K
N
N
K
Chicken
Gallus gallus
Q90632
542
58161
M222
D
K
Y
E
A
K
E
M
L
P
I
G
G
K
S
Frog
Xenopus laevis
Q6GM59
460
50319
S216
K
R
E
P
Q
L
D
S
S
C
S
P
L
C
Q
Zebra Danio
Brachydanio rerio
Q503M4
477
51835
V217
D
S
E
C
G
Y
S
V
K
P
P
T
L
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.4
93.9
81.5
N.A.
72.9
71.5
N.A.
71.7
42.6
32.2
29.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73
97.6
89.8
N.A.
85.9
85.4
N.A.
84
60.7
53.5
50.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
66.6
26.6
N.A.
26.6
26.6
N.A.
20
13.3
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
66.6
33.3
N.A.
33.3
46.6
N.A.
26.6
26.6
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
20
0
10
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
10
0
0
0
10
0
% C
% Asp:
20
0
0
0
0
50
40
10
0
10
0
0
0
0
10
% D
% Glu:
0
10
20
10
30
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
40
0
10
10
10
0
10
10
0
10
10
10
0
10
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
10
0
20
0
0
% I
% Lys:
20
10
10
0
0
20
0
0
20
20
30
30
20
60
10
% K
% Leu:
0
0
0
10
0
10
0
0
20
10
10
10
20
0
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
0
0
10
20
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
30
10
10
0
0
10
% P
% Gln:
0
0
0
0
20
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
0
10
0
30
0
0
0
0
0
0
10
0
0
10
0
% R
% Ser:
0
10
30
0
0
0
30
50
40
10
10
0
20
0
10
% S
% Thr:
20
0
10
20
0
0
0
10
10
0
0
20
0
0
10
% T
% Val:
30
10
0
0
10
0
0
10
0
0
10
10
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _