KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REV3L
All Species:
16.06
Human Site:
S279
Identified Species:
44.17
UniProt:
O60673
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60673
NP_002903.3
3130
352776
S279
R
R
N
R
N
E
T
S
Q
M
S
Q
P
E
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086055
3130
352672
S279
R
R
N
R
N
E
T
S
Q
I
S
Q
P
E
S
Dog
Lupus familis
XP_539084
3058
344677
V244
S
V
T
L
S
G
S
V
D
Y
S
D
G
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61493
3122
350641
S279
R
R
N
R
N
E
S
S
Q
I
S
Q
P
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520025
1544
171107
Chicken
Gallus gallus
XP_426179
3135
353106
S268
R
R
E
K
C
E
S
S
Q
I
K
T
P
E
S
Frog
Xenopus laevis
NP_001163919
3139
352589
S281
R
R
E
K
R
E
S
S
Q
I
S
P
P
D
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786092
3425
381348
D299
R
E
Q
L
D
Q
M
D
Q
L
L
P
P
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14284
1504
172939
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.4
90
N.A.
86.5
N.A.
N.A.
35.1
72.3
58.1
N.A.
N.A.
N.A.
N.A.
N.A.
31.5
Protein Similarity:
100
N.A.
97.9
92.9
N.A.
91.8
N.A.
N.A.
41.4
82.8
72.4
N.A.
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
N.A.
93.3
6.6
N.A.
86.6
N.A.
N.A.
0
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
N.A.
100
20
N.A.
100
N.A.
N.A.
0
73.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
12
12
0
0
12
0
12
0
% D
% Glu:
0
12
23
0
0
56
0
0
0
0
0
0
0
45
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
45
0
0
0
0
0
% I
% Lys:
0
0
0
23
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
0
0
0
23
0
0
0
0
0
12
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
34
0
34
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
23
67
0
0
% P
% Gln:
0
0
12
0
0
12
0
0
67
0
0
34
0
0
12
% Q
% Arg:
67
56
0
34
12
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
12
0
45
56
0
0
56
0
0
23
67
% S
% Thr:
0
0
12
0
0
0
23
0
0
0
0
12
0
0
0
% T
% Val:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _