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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REV3L All Species: 14.55
Human Site: Y75 Identified Species: 40
UniProt: O60673 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60673 NP_002903.3 3130 352776 Y75 Y G Q Q P E S Y L S Q M A F S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086055 3130 352672 Y75 Y G Q Q P E S Y L S Q M A F S
Dog Lupus familis XP_539084 3058 344677 P74 I M N K F Y Q P H E A H I P Y
Cat Felis silvestris
Mouse Mus musculus Q61493 3122 350641 Y75 Y G Q Q P E S Y L S Q M A F S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520025 1544 171107
Chicken Gallus gallus XP_426179 3135 353106 A79 I D R A L N V A L G N P S S T
Frog Xenopus laevis NP_001163919 3139 352589 Y76 G Q Q D P E R Y L R Q I A F S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786092 3425 381348 Y74 G S Q P T D R Y L H Q M A S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P14284 1504 172939
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.4 90 N.A. 86.5 N.A. N.A. 35.1 72.3 58.1 N.A. N.A. N.A. N.A. N.A. 31.5
Protein Similarity: 100 N.A. 97.9 92.9 N.A. 91.8 N.A. N.A. 41.4 82.8 72.4 N.A. N.A. N.A. N.A. N.A. 47.3
P-Site Identity: 100 N.A. 100 0 N.A. 100 N.A. N.A. 0 6.6 60 N.A. N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 N.A. 100 6.6 N.A. 100 N.A. N.A. 0 26.6 66.6 N.A. N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 0 12 0 0 12 0 56 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 12 0 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 45 0 0 0 12 0 0 0 0 0 % E
% Phe: 0 0 0 0 12 0 0 0 0 0 0 0 0 45 0 % F
% Gly: 23 34 0 0 0 0 0 0 0 12 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 12 12 0 12 0 0 0 % H
% Ile: 23 0 0 0 0 0 0 0 0 0 0 12 12 0 0 % I
% Lys: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 12 0 0 0 67 0 0 0 0 0 0 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 45 0 0 0 % M
% Asn: 0 0 12 0 0 12 0 0 0 0 12 0 0 0 0 % N
% Pro: 0 0 0 12 45 0 0 12 0 0 0 12 0 12 0 % P
% Gln: 0 12 56 34 0 0 12 0 0 0 56 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 23 0 0 12 0 0 0 0 0 % R
% Ser: 0 12 0 0 0 0 34 0 0 34 0 0 12 23 56 % S
% Thr: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 12 % T
% Val: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 34 0 0 0 0 12 0 56 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _