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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT3
All Species:
17.27
Human Site:
S171
Identified Species:
31.67
UniProt:
O60678
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60678
NP_005779.1
531
59903
S171
H
M
E
A
R
A
L
S
A
E
A
A
L
A
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092890
531
59784
S171
C
M
E
A
R
A
L
S
A
E
A
E
L
A
R
Dog
Lupus familis
XP_534089
541
60618
S181
H
M
E
A
R
A
L
S
A
E
A
A
L
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q922H1
532
59884
S169
H
M
E
A
R
A
L
S
A
E
A
A
L
A
R
Rat
Rattus norvegicus
O70467
528
59401
S169
L
M
E
A
R
A
L
S
A
E
A
A
L
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505718
571
63850
A211
H
T
E
A
R
A
Q
A
A
E
A
A
L
A
R
Chicken
Gallus gallus
XP_420907
526
59430
L167
H
A
E
H
R
A
R
L
A
E
A
A
L
A
R
Frog
Xenopus laevis
Q8AV13
369
42306
G37
N
S
A
P
P
E
G
G
V
K
T
N
A
E
D
Zebra Danio
Brachydanio rerio
Q5RGQ2
419
48204
A87
C
P
G
R
G
K
M
A
K
L
L
N
P
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396035
525
60169
A173
Q
L
E
Q
R
E
L
A
C
F
L
A
K
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192186
519
58632
R169
K
E
L
V
E
L
R
R
K
V
R
C
L
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82210
366
41153
N34
S
M
H
D
G
D
D
N
N
A
D
V
A
D
D
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
L16
S
A
T
E
K
T
K
L
S
E
S
E
Q
H
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.1
90.9
N.A.
89.8
89.2
N.A.
78.8
70.8
35.4
35.7
N.A.
N.A.
42.5
N.A.
45
Protein Similarity:
100
N.A.
96.8
95.1
N.A.
93.9
93.9
N.A.
85.9
83.2
49.1
52.3
N.A.
N.A.
62.5
N.A.
63.6
P-Site Identity:
100
N.A.
86.6
100
N.A.
100
93.3
N.A.
80
73.3
0
0
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
N.A.
86.6
100
N.A.
100
93.3
N.A.
86.6
73.3
13.3
13.3
N.A.
N.A.
46.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
47
0
54
0
24
54
8
54
54
16
54
0
% A
% Cys:
16
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
0
8
8
0
0
0
8
0
0
8
16
% D
% Glu:
0
8
62
8
8
16
0
0
0
62
0
16
0
24
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
8
0
16
0
8
8
0
0
0
0
0
0
0
% G
% His:
39
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
8
8
0
16
8
0
0
8
0
0
% K
% Leu:
8
8
8
0
0
8
47
16
0
8
16
0
62
0
0
% L
% Met:
0
47
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
8
0
0
16
0
0
0
% N
% Pro:
0
8
0
8
8
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
8
0
0
8
0
0
0
0
0
8
8
8
% Q
% Arg:
0
0
0
8
62
0
16
8
0
0
8
0
0
0
54
% R
% Ser:
16
8
0
0
0
0
0
39
8
0
8
0
0
0
0
% S
% Thr:
0
8
8
0
0
8
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
8
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _